research Regulation of somatic cell reprogramming through inducible mir-302 expression
Increasing mir-302 turns human hair cells into stem cells by changing gene regulation and demethylation.
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research The Expanded “Flying-Wings” Scalp Flap for Aesthetic Hemiscalp Alopecia Reconstruction in Children
The "flying-wings" scalp flap technique is a simple, safe, and effective way to reconstruct large areas of scalp loss in children.
research In-vitro and In-vivo Characterization of Bio-Patch to Hydrogel on Skin Wounds for Efficient Scarless Wound Healing
The bio-patch promotes faster, scarless wound healing.
research Lifestyle and Physiological Factors Associated with Facial Wrinkling in Men and Women
Age, smoking, and lower BMI increase facial wrinkles; men wrinkle more than women, except in old age; pale skin and certain hormonal factors can protect against wrinkles.
research Safety of 5α-reductase inhibitors and spironolactone in breast cancer patients receiving endocrine therapies
The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
research Low-Dose Systemic Methotrexate Therapy for Recalcitrant Alopecia Areata
Low-dose methotrexate effectively regrows hair in many alopecia areata patients but can cause some side effects.
research Overexpression of alkaline phosphatase improves the hair-inductive capacity of cultured human dermal papilla spheres
Increasing alkaline phosphatase in human skin cells helps to grow more hair.
research A falling out following minoxidil: Telogen effluvium
A man lost a lot of scalp hair quickly after stopping minoxidil, but it grew back with mild male pattern baldness.
research EXPERIENCE WITH ANIFROLUMAB IN SYSTEMIC LUPUS ERYTHEMATOSUS PATIENTS WITH NEUROLOGICAL MANIFESTATIONS
Anifrolumab helped some lupus patients reduce steroid use, but safety concerns remain.
research Morphologic Markers of Acute and Chronic Stress in Child Abuse
The conclusion is that certain physical signs in the body can indicate past acute and chronic stress, which may help in child abuse investigations.
research Novel type 1 5a-reductase Inhibitors with Antiproliferative Potential on LNCaP cells
New compounds may help treat prostate cancer by reducing cell growth.
research A case of unusual comedogenesis in alopecia totalis
A man with total hair loss developed blackhead-like spots on his scalp, possibly because no hair was present to help drain oils.
research Androstanediolglucuronide: A parameter for peripheral androgen activity before and during therapy with cyproterone acetate
3α-AdiolG is a good marker for androgen activity in women with excessive hair growth and decreases with anti-androgen treatment.
research Topical Application of Magnetized Saline Water Hydrogel Promotes Rapid Pressure Ulcer Healing in Hospitalized Elderly Patients: An Acute Care Case Series
Magnetized saline water hydrogel helps heal pressure ulcers quickly in elderly patients.
research Synthesis of phenanthridin-3-one derivatives: Non-steroidal inhibitors of steroid 5-α-reductase
New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
research Comparative Efficacy of Topical Calcipotriol, Intralesional Autologous Platelet-Rich Plasma Injection, and Combined Topical Calcipotriol with Intralesional Autologous Platelet-Rich Plasma Injection on Patients with Alopecia Areata
The combination of calcipotriol and PRP is the most effective treatment for alopecia areata.
research Quantifying whole human hair scalp fibres of varying curl: A micro‐computed tomographic study
Human hair varies in structure based on curl type, with high curl hair showing the most differences.
research Clinicopathologic features, demographics, disease burden, and therapeutics in alopecic sarcoidosis: a case series and systematic review
Early diagnosis and thorough evaluation are crucial for better outcomes in alopecic sarcoidosis.
research New approach to 3-oxo-4-aza-5α-androst-1-ene-17β-(--butylcarboxamide)
A new method was developed to make finasteride for treating hair loss.
![Synthesis and In Vitro Study of 17β-[N-Ureylene-N,N′-Disubstituted]-4-Methyl-4-Aza-5α-Androstan-3-Ones as Selective Inhibitors of Type I 5α-Reductase](/images/research/d19df8a7-8de6-4430-8a0d-4ffa1f502985/small/15608.jpg)
research Synthesis and in vitro study of 17β-[N-ureylene-N,N′-disubstituted]-4-methyl-4-aza-5α-androstan-3-ones as selective inhibitors of type I 5α-reductase
New compounds were made that effectively block a specific enzyme related to androgen conditions.
research Deletion of the Developmentally Essential Gene ATR in Adult Mice Leads to Age-Related Phenotypes and Stem Cell Loss
Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
research Chronic administration of minoxidil protects elastic fibers and stimulates their neosynthesis with improvement of the aorta mechanics in mice
Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.
research Exploring the efficacy of baricitinib in treating alopecia areata after failed Janus kinase inhibitor therapy
Baricitinib helped regrow hair in patients with severe alopecia areata after other treatments failed.
research MiR-23b and miR-133 Cotarget TGFβ2/NOTCH1 in Sheep Dermal Fibroblasts, Affecting Hair Follicle Development
MiR-23b and miR-133 affect sheep hair growth by targeting specific genes.
research Ex vivo dermatoscopy of scalp specimens and slides
Ex vivo dermatoscopy may lower lab costs and improve diagnosis speed for hair loss biopsies.
research Author response: The signaling lipid sphingosine 1-phosphate regulates mechanical pain
Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
research Preparation, Characterization and Molecular Docking Study of some New Pyrazole Derivatives Derived from 2-Mercaptobenzothiazole.
New pyrazole derivatives may help treat hair loss, but more testing is needed.
research Degree of Alignment Between Japanese Patients and Physicians on Alopecia Areata Disease Severity and Treatment Satisfaction: A Real-World Survey
Japanese patients and physicians often disagree on the severity of Alopecia Areata and treatment satisfaction, needing better communication and treatments.
research 17beta Hydroxysteroid Dehydrogenase Type 3 Inhibitors
The document's conclusion cannot be provided because the document is not available or cannot be read.
research Cortexolone 17a-propionate: A new antiandrogen acting on hair dermal papilla cells for the treatment of androgenic alopecia
Cortexolone 17a-propionate may be an effective new treatment for hair loss.