43 citations
,
July 2017 in “International journal of pharmaceutics” Using β-cyclodextrin derivatives improves the solubility and bioavailability of steroidal drugs.
17 citations
,
October 1994 in “The Journal of Clinical Endocrinology and Metabolism” October 2019 in “Bioscientifica Proceedings” Androgens may improve pig reproduction by enhancing ovulation and litter size.
January 2026 in “Journal of Sexual and Mental Health” New male contraceptive pills show promise in reducing sperm production with mild side effects.
December 2022 in “CRC Press eBooks” Antiandrogens block male hormones and are not safe during pregnancy.
52 citations
,
April 2002 in “Brain Research” Lower allopregnanolone levels increase stress-related dopamine release in the brain.
January 2002 in “NCSU Libraries Repository (North Carolina State University Libraries)” 17b-Estradiol in skin affects hair growth and tumor promotion.
August 2016 in “Journal of Investigative Dermatology” 22 citations
,
December 1991 in “PubMed” June 2021 in “F1000Research” Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.
March 2020 in “StatPearls” Medicines called 5-alpha-reductase inhibitors, like finasteride and dutasteride, are useful for treating enlarged prostate and male pattern hair loss.
January 2023 in “Pharmaceutics” AA–TF#15 significantly promotes hair regrowth and could be an effective treatment for androgenic alopecia.
14 citations
,
September 1986 in “Archives of Dermatology” Women with low SHBG levels and a high 3a-diol G to SHBG ratio are likely to experience female pattern baldness, possibly due to a slight excess of androgens affecting sensitive hair bulbs.
January 2018 in “Surgical and Cosmetic Dermatology” 5-alpha reductase inhibitors like finasteride and dutasteride are effective for treating enlarged prostate and male pattern hair loss.
February 2014 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Dutasteride 0.5mg is more effective than finasteride 1mg for treating male pattern baldness.
1 citations
,
December 1992 in “International Journal of Dermatology” No significant hormone differences found in postmenopausal women with androgenetic alopecia.
235 citations
,
September 2004 in “The Journal of urology/The journal of urology” Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.
August 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Androgenetic alopecia in males is linked to hormone levels and the enzyme 5-alpha reductase.
15 citations
,
October 2016 in “Steroids” Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.
November 2021 in “Revista Ibero-Americana de Humanidades, Ciências e Educação” The document does not give specific results for hair loss treatment effectiveness.
58 citations
,
July 1974 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Cyproterone acetate combined with ethinyl estradiol significantly reduced hirsutism in women.
20 citations
,
September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
June 2013 in “Lithuanian University of Health Sciences” January 2025 in “Journal of Ethnopharmacology” Dahuang-Gancao Decoction improves hair growth in androgenetic alopecia.
July 2025 in “Journal of Investigative Dermatology” 5% ET-02 is a more effective and safe treatment for hair loss than current options.
269 citations
,
May 2002 in “Hormones and Behavior” Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
14 citations
,
August 2007 in “Bioorganic & Medicinal Chemistry Letters” The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.
77 citations
,
June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
7 citations
,
April 2009 in “Bioorganic & Medicinal Chemistry Letters” Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.