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The authors suggest that 5-α-reductase inhibitors, like dutasteride, are effective in treating frontal fibrosing alopecia and should be the first-line treatment, with other options for severe cases. They also recommend further research on Janus kinase inhibitors.

Spironolactone reduces hair growth in women with unexplained excessive hairiness.

Sex hormone therapy is effective for certain skin conditions like acne and seborrhea, but less so for female hair loss and excessive hair growth.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

DHT deficiency in rats reduces sperm content and affects testis structure over time.

Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Scalp hair 17-OHP and androstenedione levels can help monitor treatment in CAH patients.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.

Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.

Finasteride treatment changes hormone levels in male pattern baldness patients.

Clascoterone may be an effective topical treatment for hair loss.

Taking 5-alpha reductase inhibitors does not increase the risk of breast cancer in men.

The chemicals 17βC and its methyl ester can block the effects of testosterone on hamster skin but not the effects of DHT.

Male pattern baldness is likely caused by multiple genes, not just 5α-reductase genes.

A new system helps better diagnose and treat female androgenization conditions like PCOS.

RXR agonists may promote hair growth in humans.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

A woman with a specific mutation causing adrenal gland issues faced fertility problems, but careful hormone therapy helped her manage it successfully.

Reversing female hair loss.

Finasteride breaks down into new compounds under acidic conditions.

A specific gene mutation causes vitamin D resistance, but certain vitamin D analogs might help.