7 citations
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January 2013 in “European Urology” 5-Alpha reductase inhibitors may prevent prostate cancer but are not widely used due to concerns about trial relevance and potential risks, and more research is needed to confirm long-term benefits.
3 citations
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September 2020 in “Bladder cancer” 5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.
42 citations
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December 1976 in “PubMed” Cyproterone acetate and ethinylestradiol effectively reduce hirsutism and acne in women.
January 2011 in “The Journal of Secondary Vocational Education” Isotretinoin treatment in teens with acne can cause hormonal changes, leading to menstrual irregularity and increased hirsutism.
42 citations
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May 2007 in “Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism” Testosterone can build muscle and bone without enlarging the prostate when a specific enzyme is blocked.
5 citations
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January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
4 citations
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September 2006 in “European Urology Supplements” Dutasteride reduces DHT and improves BPH symptoms more effectively than finasteride.
32 citations
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July 2016 in “PubMed” 5-alpha reductase inhibitors are generally safe but can cause sexual side effects and require patient education on risks.
12 citations
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January 2010 in “Acta Dermato Venereologica” Women with early onset androgenetic alopecia have worse lipid profiles.
46 citations
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October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
A balanced diet is crucial for normalizing hormone levels and managing obesity-related issues.
March 2016 in “European Urology Supplements” Methylation in specific gene region causes finasteride resistance in some BPH patients.
29 citations
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July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.
4 citations
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November 2024 in “The Journal of Steroid Biochemistry and Molecular Biology” 9 citations
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August 2021 in “Biomedicines” 17β-estradiol boosts APE1/Ref-1 secretion in cells and mice via a calcium-dependent pathway.
31 citations
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August 2001 in “PubMed” Hair follicles convert androgens, affecting hair loss patterns.
May 2026 in “RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218” Post-Finasteride Syndrome causes lasting sexual, mood, and metabolic issues, needing personalized treatment and better informed consent.
May 2003 in “Journal of Investigative Dermatology” The meeting covered advances in understanding hair growth, causes of hair loss, and potential treatments.
12 citations
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March 2000 in “Clinical Chemistry” Chronic DHEA supplementation slightly increases testosterone in hair but stays within safe limits.
May 2023 in “Frontiers in Endocrinology” Blocking CRF1 receptors improved male hormone levels and reduced testicular tumor size in men with a specific adrenal condition.
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
5 citations
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July 2025 in “Endocrine”
8 citations
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May 1996 in “Endocrinology” Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.
March 2023 in “Journal of Drugs in Dermatology” Hormonal therapies, especially antiandrogens, can help manage Hidradenitis Suppurativa.
27 citations
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November 1998 in “Journal of Endocrinological Investigation” Finasteride significantly reduces hair growth in women with idiopathic hirsutism.
December 2022 in “Acta Ophthalmologica” Dutasteride potentially improves cell survival and reduces retinal damage in retinitis pigmentosa.
Dutasteride may become the top choice for treating hair loss.
40 citations
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October 2004 in “Veterinary Dermatology” Trilostane treatment led to full hair regrowth in most Pomeranians and all miniature poodles with alopecia X.
2 citations
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April 2021 in “Canadian Journal of Urology” Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
June 2021 in “Research Square (Research Square)” Statins significantly reduce testosterone and improve skin symptoms in women with PCOS.