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Glossary3D Imaging

technology that creates visual representations in three dimensions

3D Imaging, or Three-Dimensional Imaging, is a technology that creates a visual representation of objects in three dimensions, allowing for depth perception similar to how human vision works. This technique is widely used in various fields, including medicine for detailed anatomical studies, in biology for visualizing complex structures like hair follicles, and in dermatology for assessing conditions such as alopecia.

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research LB1605 3D imaging of cleared ex vivo normal human skin, skin appendages and psoriasiform skin lesion using light-sheet microscopy

August 2018 in “Journal of Investigative Dermatology”

The conclusion is that using light-sheet fluorescence microscopy with a special solution can effectively create detailed 3D images of human skin for dermatological research.

Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages

September 2017 in “Journal of Investigative Dermatology”

Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.

research 710 Use of mass spectrometry imaging and a full thickness 3D skin equivalent for evaluation of percutaneous absorption

April 2017 in “Journal of Investigative Dermatology”

The document concludes that various topical treatments show promise for skin conditions like atopic dermatitis, psoriasis, and hair loss.

research Novel approaches to characterize age‐related remodelling of the dermal‐epidermal junction in 2D, 3D and in vivo

30 citations , August 2016 in “Skin research and technology”

3D imaging shows clearer details of skin structure changes with age.

research Three‐dimensional imaging and analysis of the surface of hair fibres using scanning electron microscopy

14 citations , July 2007 in “International Journal of Cosmetic Science”

The new 3D imaging method accurately measures hair surface details quickly.

research Research Techniques Made Simple: Optical Clearing and Three-Dimensional Volumetric Imaging of Skin Biopsies

2 citations , June 2020 in “Journal of Investigative Dermatology”

3D imaging of skin biopsies offers better accuracy but is time-consuming and can't clear melanin.

research Three-dimensional imaging for facial vitiligo: Results from a phase 2 randomized controlled trial investigating upadacitinib in patients with vitiligo

January 2026 in “Journal of Investigative Dermatology”

3D imaging effectively tracks skin changes in vitiligo treatment.

research Photoacoustic Imaging as a Tool for Assessing Hair Follicular Organization

11 citations , October 2020 in “Sensors”

Photoacoustic imaging can accurately assess hair follicle density and orientation for hair transplant planning.

research Overview of Facial Plastic Surgery and Current Developments

38 citations , February 2016 in “Surgery Journal”

Facial plastic surgery has evolved to focus on less invasive techniques and innovative technologies for cosmetic and reconstructive procedures.

research Touch Receptors Undergo Rapid Remodeling in Healthy Skin

31 citations , November 2016 in “Cell Reports”

Touch sensitivity in mouse skin decreases during hair growth due to changes in touch receptors.

research Confocal Laser Scanning Microscopy as a Tool for the Investigation of Skin Drug Delivery Systems and Diagnosis of Skin Disorders

4 citations , March 2013 in “InTech eBooks”

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

research 1412 “Telescope model” for coordinated organ morphogenesis and stem cell formation

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Developing hair follicles form from ring-shaped patterns, with future stem cells originating from the outer ring, not the upper layers, as previously thought.

research 203 Automated skin surface phenotype for melanoma risk assessment

April 2023 in “Journal of Investigative Dermatology”

An automated method accurately assesses melanoma risk using 3D body images to analyze skin traits.

Skin Organoids Derived From NCSTN Mutated Patient-Induced Pluripotent Stem Cells Recapitulate Hidradenitis Suppurativa Pathogenic Hallmarks

research 545 Skin Organoids derived from NCSTN mutated patient-induced pluripotent stem cells recapitulate Hidradenitis Suppurativa pathogenic hallmarks

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.

Hair Follicles Employ a Two-Dimensional Healing Strategy to Repair Three-Dimensional Injuries

research 573 Hair follicles employ a 2-dimensional healing strategy to repair 3-dimensional injuries

September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology”

Hair follicles repair 3D injuries using a 2D healing process.

research Microscopic high-resolution digital volumetric imaging of human hair fibers

March 2005 in “International Journal of Cosmetic Science”

DVI provides detailed 3D imaging of hair and shows how various products protect and enhance hair.

research Streamlined Intravital Imaging Approach for Long-Term Monitoring of Epithelial Tissue Dynamics on an Inverted Confocal Microscope

1 citations , June 2023 in “Journal of Visualized Experiments”

A new 3D-printed microscope stage makes long-term imaging of live tissue easier and more accessible.

research Three-dimensional model of normal human dermal tissue using serial tissue sections

5 citations , March 2024 in “Frontiers in Bioengineering and Biotechnology”

A detailed 3D model of human skin was created to help develop artificial skin.

research Streamlined intravital imaging approach for long-term monitoring of epithelial cell dynamics on an inverted confocal microscope

1 citations , May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

A new tool allows easier long-term imaging of live skin cells, helping study diseases like skin cancer.

research 3D bioprinting in plastic and reconstructive surgery: current concepts, progress, and clinical application

August 2023 in “European Journal of Plastic Surgery”

3D bioprinting is advancing in plastic and reconstructive surgery, especially for creating tissues and improving surgical planning, but faces challenges like vascularization and material development.

Immunofluorescence Tomography: High-Resolution 3D Reconstruction by Serial-Sectioning of Methacrylate Embedded Tissues and Alignment of 2D Immunofluorescence Images

research Immunofluorescence Tomography: High-resolution 3-D reconstruction by serial-sectioning of methacrylate embedded tissues and alignment of 2-D immunofluorescence images

8 citations , February 2019 in “Scientific Reports”

Immunofluorescence tomography is a cost-effective method for creating detailed 3-D images of tissues.

research Feature identification of skin diseases and laser therapy with a portable optical coherence imaging system

September 2023

A portable imaging system shows promise for diagnosing skin diseases and checking laser treatment effects.

research RoPod, a customizable toolkit for non-invasive root imaging, reveals cell type-specific dynamics of plant autophagy

6 citations , June 2024 in “Scientific Reports”

RoPod helps study plant root cell changes and autophagy with minimal stress.

Multi-View Light Sheet Fluorescence Microscopy for Imaging Cellular Self-Assembly in Spheroids of Human Hair Follicle Dermal Papilla Cells and Keratinocytes

research 812 Multi-view light sheet florescence microscopy (LSFM) for imaging cellular self-assembly in spheroids of human hair follicle dermal papilla cells and keratinocytes

June 2020 in “Journal of Investigative Dermatology”

The technique effectively shows how human skin and hair cells form into ball-like structures.

Hydroxysteroid Dehydrogenase (17β-HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors: Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels

20 citations , June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery”

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

research Microencapsulated cell tracking

33 citations , December 2012 in “NMR in Biomedicine”

Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.