research Lactate dehydrogenase activity drives hair follicle stem cell activation
Lactate production is important for activating hair growth stem cells.
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research Expansion and characterization of epithelial stem cells with potential for cyclical hair regeneration
A specific group of stem cells can help regenerate hair continuously.
research Small molecules and small molecule drugs in regenerative medicine
Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
research Tissue engineering strategies for human hair follicle regeneration: How far from a hairy goal?
Fully regenerating human hair follicles not yet achieved.
research Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue cells
A new method using human lung cells helps find drugs to block and reduce inflammation from SARS-CoV-2.
research Extracellular vesicle-based drug overview: research landscape, quality control and nonclinical evaluation strategies
Extracellular vesicles show promise for treating diseases but face challenges in development and regulation.
research Glutamine Metabolism Controls Stem Cell Fate Reversibility and Long-Term Maintenance in the Hair Follicle
Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
research Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear
Stem cell therapy could help regenerate inner ear hair cells to treat hearing loss.
research Epidermal Stem Cells in Hair Follicle Cycling and Skin Regeneration: A View From the Perspective of Inflammation
Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
research Current Status of the Applications of Conditioned Media Derived from Mesenchymal Stem Cells for Regenerative Medicine
Conditioned media from mesenchymal stem cells show promise for tissue repair and disease treatment, but more research is needed on their safety and effectiveness.
research CD4 expression controls epidermal stem cell balance
CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
research Microneedles: A Promising Therapeutic Strategy for Next-Generation Drug Delivery, Diagnosis and Biosensing
Microneedles offer a painless, precise, and versatile method for drug delivery and disease treatment.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Paneth Cells in Intestinal Homeostasis and Tissue Injury
Paneth cells help support stem cells and aid tissue regeneration after injury.
research Signaling in the stem cell niche: regulating cell fate, function and plasticity
The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.
research Repairing the lungs one breath at a time: How dedicated or facultative are you?
Lung repair involves both dedicated and flexible stem cells, important for developing new treatments.
research A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration
Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
research Adiponectin Signaling Regulates Lipid Production in Human Sebocytes
Adiponectin boosts lipid production in skin cells, potentially helping treat skin conditions with low sebum.
research Therapeutic Potential of Patient iPSC-Derived iMelanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
research The Hair Follicle: An Underutilized Source of Cells and Materials for Regenerative Medicine
Hair follicles are valuable for regenerative medicine and wound healing.
research Inducing hair follicle neogenesis with secreted proteins enriched in embryonic skin
Three specific proteins can turn adult skin cells into hair-growing cells, suggesting a new hair loss treatment.
research Recent updates on Wnt signaling modulators: a patent review (2014-2020)
New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.
research Human Fetal Scalp Dermal Papilla Enriched Genes and the Role of R-Spondin-1 in the Restoration of Hair Neogenesis in Adult Mouse Cells
Certain genes are more active in baby scalp cells and can help grow hair when added to adult mouse skin cells.
research From bedside to bench: regulation of host factors in SARS-CoV-2 infection
The conclusion is that certain genetic factors and blood types may affect COVID-19 severity, but changes in ACE2 and TMPRSS2 genes are not clearly linked to it.
research Role of the Wnt signaling pathway in keratoacanthoma
The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.
research Keeping up with the neighbours: local synchronisation of cell fate decisions during development
Cells communicate with neighbors to coordinate their development.
research Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
research New insights into the functions of Cox-2 in skin and esophageal malignancies
Cox-2 significantly contributes to the development and progression of skin and esophageal cancers.
research Computational screening of repurposed drugs and natural products against SARS-Cov-2 main protease (Mpro) as potential COVID-19 therapies
Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.
research A new look into an old problem: keratins as tools to investigate determination, morphogenesis, and differentiation in skin.
Keratin expression reflects cell organization and differentiation, not causes it.