135 citations
,
December 2006 in “PLoS Medicine” Hyaluronate fragments can help reverse skin thinning by working with the CD44 receptor.
9 citations
,
October 1976 in “Journal of Cutaneous Pathology” Human growth hormone treatment improved skin thickness and structure in osteoporosis patients.
20 citations
,
September 2015 in “Protein expression and purification” Scientists made safflower seeds produce a human growth factor that could help with hair growth and wound healing.
December 2024 in “The Journal of Cell Biology” Basement membrane changes are crucial for hair follicle development.
January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” IGF-I helps hair growth by preventing cell death and boosting growth factors.
July 2022 in “Research Square (Research Square)” Huaier helps hair grow back and repairs tissue after cancer treatment.
37 citations
,
July 1999 in “The EMBO Journal” Overexpression of certain genes can shorten hair by disrupting the hair-growth cycle.
1 citations
,
October 2025 in “International Journal of Molecular Sciences” Mutating the gmds gene in zebrafish increases hair cell numbers and regeneration.
8 citations
,
April 1997 in “Experimental Dermatology” hHbl gene is active in hair shaft cells and some pilomatricomas.
23 citations
,
March 2019 in “Gene” Editing the FGF5 gene in sheep increases wool length, confirming its role in hair growth.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Human hair follicles can be used to create heart muscle cells.
February 2022 in “Research Square (Research Square)” A protein made in a plant stopped hair growth in mice.
3 citations
,
July 2024 in “Cell Proliferation” Blocking TGFβ can help treat fibrotic skin conditions by promoting fat cell formation.
1 citations
,
April 2022 in “Regenerative Therapy” Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.
125 citations
,
February 2007 in “The EMBO Journal” Fgfr2b helps maintain healthy skin and prevent cancer.
December 2025 in “Plastic & Reconstructive Surgery” The treatment effectively reduces hair loss and improves hair growth with minimal side effects.
August 2024 in “Biomolecules & Therapeutics” A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
323 citations
,
November 1984 in “Journal of Investigative Dermatology” 32 citations
,
December 2015 in “PloS one” P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
2 citations
,
January 2022 in “Experimental Dermatology” GDNF signaling helps in hair growth and skin healing after a wound.
January 2017 in “PRISM (University of Calgary)” Unique genes in hair follicle cells help tissue regeneration.
April 2021 in “Journal of Investigative Dermatology” A trial showed that a new treatment is safe and effective for male pattern baldness, with most participants growing new hair.
April 2013 in “Developmental Cell” Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
23 citations
,
June 2012 in “PLOS ONE” KLF4 is important for maintaining skin stem cells and helps heal wounds.
1 citations
,
April 1998 in “PubMed” 46 citations
,
June 2013 in “Journal of structural biology” High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
25 citations
,
January 2017 in “Steroids” Allopregnanolone increases growth and changes gene activity in human brain cancer cells.
44 citations
,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
April 2018 in “Journal of Investigative Dermatology” DPP4 is important for scarring and skin regeneration, and managing its activity could improve skin healing treatments.