149 citations
,
January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
27 citations
,
May 2008 in “Neuroscience” Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.
23 citations
,
July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain chemicals and peptides can promote hair growth or prevent baldness.
20 citations
,
January 2004 in “PubMed” Dutasteride reduces DHT more than finasteride, but both drugs improve BPH symptoms similarly.
9 citations
,
January 2009 in “PubMed” Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
3 citations
,
March 2014 in “Turkderm” Hair loss in men can be slowed or reversed with treatments like minoxidil and finasteride, but it resumes if treatment stops. It may also indicate early heart disease and obesity.
January 2019 in “Oncogen” Triple Hormonal Blockade (ADT3) can effectively manage prostate cancer but requires careful monitoring for heart risks.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
February 2017 in “Vestnik dermatologii i venerologii” Hair loss can be treated with common methods like minoxidil and finasteride, but new potential treatments include growth factors, cytokines, and platelet-rich plasma injections.
35 citations
,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
33 citations
,
January 2009 in “Contraception” Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
153 citations
,
April 2009 in “Urology” Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.
November 2011 in “Nature Clinical Practice Urology” 5ARIs effectively treat and manage BPH by reducing prostate size and symptoms.
May 2022 in “Endocrine Abstracts” Finasteride may cause sexual dysfunction by reducing epinephrine levels.
February 2021 in “Reactions Weekly” Finasteride and dutasteride may cause macular abnormalities.
November 2020 in “Reactions Weekly” Finasteride can cause lasting erectile dysfunction, low libido, and depression in some patients.
56 citations
,
February 2006 in “American journal of physiology. Cell physiology” Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
September 2017 in “Journal of Investigative Dermatology” Researchers created human cells that can turn into sebocytes, which may help study and treat skin conditions like acne.
80 citations
,
January 1995 in “The American Journal of Medicine” Hair loss in androgenetic alopecia is caused by genetic factors and androgen excess, and can be treated with combined therapies.
49 citations
,
April 2012 in “Phytotherapy Research” Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
48 citations
,
January 2003 Endophytes from Southeast Asia and Japan can produce useful substances like enzymes and antibiotics.
16 citations
,
April 2017 in “Journal of Cosmetic Dermatology” Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
14 citations
,
January 2019 in “Journal of Natural Medicines” Chaga mushrooms contain compounds that may promote hair growth better than common treatments.
14 citations
,
September 1983 in “Acta Dermato Venereologica” Citral increases sebaceous gland activity in male rats.
February 2025 in “Jurnal Kesehatan Bakti Tunas Husada Jurnal Ilmu-ilmu Keperawatan Analis Kesehatan dan Farmasi” Nanostructured Lipid Carriers can improve curcumin's effectiveness for treating hair loss.
May 2024 in “Journal of cosmetic dermatology” "Dutasteride 0.5 mg daily is the most effective treatment for male hair loss."
August 2018 in “SDÜ SAĞLIK BİLİMLERİ DERGİSİ” No method fully prevents hair loss from chemotherapy, but some methods can reduce it and improve quality of life.
August 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” New treatments for common hair loss might be safer and more effective than current options.
23 citations
,
August 2018 in “Facial Plastic Surgery Clinics of North America” Using defensins to activate stem cells may improve skin aging signs without causing inflammation.
January 2007 in “日本看護学会抄録集 成人看護1” Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.