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Certain drugs like Dutasteride and Finasteride might help fight SARS-CoV-2 by increasing levels of a steroid called DHEA, which can protect the heart and increase nitric oxide to counteract the virus.

Urtica laetevirens extract significantly reduces 5α-reductase activity.

Certain Chinese herbs, especially Cacumen platycladi, can promote hair regrowth and reduce hair loss-related hormone levels in mice.

Finasteride doesn't affect erections much, but may decrease libido in men.

Some herbs show promise as antiandrogenic agents.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Teak leaf extract contains compounds that could help treat hair loss.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Men taking 5-alpha-reductase inhibitors before or after bladder cancer diagnosis had a lower risk of dying from the disease.

Testosterone's muscle-building effects do not require its conversion to DHT.

Hair loss drugs may cause sexual issues and infertility in men.

Accurate protein modeling can help develop new treatments for prostate cancer and other diseases.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Long-term use of a certain medication can worsen erectile function in aged rats by damaging penile muscle cells.

New compounds may help treat prostate issues without affecting androgen receptors.

A new compound effectively inhibits human 5α-reductase 1.

New chemical compounds were made that effectively block an enzyme linked to prostate growth.

Men over 66 taking medication for prostate enlargement have a higher risk of depression and self-harm, especially in the first 18 months of treatment.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New compounds may soon be tested to treat excessive hair growth in women.

Plant-based compounds may offer safer prostate cancer treatment with fewer side effects.

Phytochemicals may offer safer alternatives to synthetic drugs for prostate cancer treatment.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Curcuma aeruginosa extract combined with minoxidil effectively treats male-pattern baldness.

Using finasteride or dutasteride does not increase the risk of male breast cancer.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.