Search

for
Search:

Sort by

Research

990-1000 / 1000+ results

The 5α-Reductase Inhibitor Finasteride Increases Suicide-Related Aggressive Behaviors and Blocks Clozapine-Induced Beneficial Effects in an Animal Model of Schizophrenia

research The 5α-reductase inhibitor finasteride increases suicide-related aggressive behaviors and blocks clozapine-induced beneficial effects in an animal model of schizophrenia

12 citations , April 2018 in “Physiology & Behavior”

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

research Anti-androgenic curcumin analogues as steroid 5-alpha reductase inhibitors

12 citations , March 2017 in “Medicinal Chemistry Research”

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

research Scd1 ab-Xyk : a new asebia allele characterized by a CCC trinucleotide insertion in exon 5 of the stearoyl-CoA desaturase 1 gene in mouse

12 citations , July 2004 in “Molecular genetics and genomics”

A new mouse mutation causes skin and hair defects due to a gene change.

Dutasteride, A Novel Dual 5-Alpha Reductase Inhibitor, Reduces Serum DHT to a Greater Extent Versus Finasteride and Achieves Maximal Reduction in a Larger Proportion of Patients

research Dutasteride, a novel dual 5-A reductase inhibitor, reduces serum DHT to a greater extent versus finasteride and achieves finasteride maximal reduction in a larger proportion of patients

12 citations , February 2003 in “European Urology Supplements”

Dutasteride reduces DHT more effectively than finasteride.

research Discovery of Natural Steroid 5 Alpha-Reductase Inhibitors

11 citations , December 2018 in “Assay and Drug Development Technologies”

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Bioequivalence of a Single 10-mg Dose of Finasteride 5-mg Oral Disintegrating Tablets and Standard Tablets in Healthy Adult Male Han Chinese Volunteers: A Randomized Sequence, Open-Label, Two-Way Crossover Study

research Bioequivalence of a single 10-mg dose of finasteride 5-mg oral disintegrating tablets and standard tablets in healthy adult male Han Chinese volunteers: A randomized sequence, open-label, two-way crossover study

10 citations , October 2009 in “Clinical Therapeutics”

Finasteride 5-mg oral disintegrating tablets and standard tablets are bioequivalent in healthy adult male Han Chinese volunteers.

research A one-year observational study with minoxidil 5% solution in Germany: results of independent efficacy evaluation by physicians and patients

10 citations , March 2004 in “Journal of the American Academy of Dermatology”

The 5% minoxidil solution effectively treated hair loss with good tolerability.

research Finasteride, A Steroid 5α-Reductase Inhibitor, Does Not Affect the Oxidative Metabolism of Antipyrine

9 citations , October 1993 in “The Journal of Clinical Pharmacology”

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

research The 5α-reductase inhibitor finasteride reduces opioid self-administration in animal models of opioid use disorder

8 citations , April 2021 in “Journal of Clinical Investigation”

Finasteride reduces opioid use and withdrawal symptoms in animals.

research Co-administration of 5α-reductase Inhibitors Worsens the Adverse Metabolic Effects of Prescribed Glucocorticoids

8 citations , June 2020 in “The Journal of Clinical Endocrinology and Metabolism”

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

← Previous page