4 citations
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August 2019 in “General and Comparative Endocrinology” Male yak hair growth is influenced by DHT synthesis, which is promoted by 5α-red1 and AR during growth phases, while E2 may inhibit growth through ERα.
January 2019 in “Dermatologica Sinica” Dutasteride improved both hair loss and acne in two young men.
August 2019 in “Key engineering materials” A microemulsion with Carthamus tinctorius extract effectively inhibits 5α-reductase and improves skin and hair follicle delivery.
4 citations
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January 2006 in “PubMed” DHT deficiency may disrupt rat epididymis function by affecting estrogen receptors.
Germinated perilla seeds can naturally promote hair growth and prevent hair loss.
April 2022 in “Molecules” Teak leaf extract contains compounds that could help treat hair loss.
2 citations
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June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
26 citations
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April 2019 in “Journal of Cosmetic Dermatology” Herbal alternatives like saw palmetto and green tea may offer safe, effective treatment for hormonal hair loss.
June 2015 in “한국화장품미용학회지” AT-Grow, a natural product, might help with a common type of hair loss by reducing DHT levels.
research Acne
81 citations
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January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
47 citations
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August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
31 citations
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January 2003 in “Dermatology” Steroidogenic isoenzymes may help improve treatments for common hair loss.
18 citations
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January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.
9 citations
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August 2000 in “Journal of Periodontal Research” Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.
5 citations
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September 2009 in “Journal of Complementary and Integrative Medicine” Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
129 citations
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January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
21 citations
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January 2006 in “Pediatrics” Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.
23 citations
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April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
7 citations
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August 2021 in “Journal of the European Academy of Dermatology and Venereology” Early treatment of fibrosing alopecia in a pattern distribution may improve outcomes.
77 citations
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March 2001 in “Clinics in Dermatology” Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
14 citations
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November 2006 in “Current Medicinal Chemistry” New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.
11 citations
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May 2009 in “Medical Hypotheses” Male pattern baldness is an unintended side effect of the body's use of androgens for muscle growth, especially in those genetically prone to it.
11 citations
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February 2008 in “British journal of nursing” Idiopathic hirsutism causes excessive hair growth in women, can be treated with medication and hair removal, but cannot be fully reversed.
1 citations
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September 2016 in “Actas Dermo-Sifiliográficas” 5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.
November 2012 in “Endocrine Practice” Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.
67 citations
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July 2006 in “Clinics in Dermatology” Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.
77 citations
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June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
17 citations
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October 2015 in “Medicine and Pharmacy Reports” Animal models are crucial for learning about hair loss and finding treatments.
14 citations
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April 2019 in “International Journal of Women's Health” Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.