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Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Gene differences may affect baldness treatment response in Korean men.

Finasteride raises suicide-linked aggression and stops clozapine's positive effects in schizophrenia animals.

Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.