106 citations
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March 2014 in “BioEssays” We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.
104 citations
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May 2003 in “Endocrinology” Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.
67 citations
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December 2019 in “PloS one” Beta-caryophyllene helps improve wound healing in mice, especially in females.
32 citations
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July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
23 citations
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September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
19 citations
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March 2018 in “Journal of Investigative Dermatology” The gene Msx2 is crucial for hair follicle regeneration during wound healing.
9 citations
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January 2016 in “International Journal of Medical Sciences” Increasing Wnt10b levels can help grow new hair follicles in mice.
2 citations
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June 2022 in “Scientific reports” Mouse hair follicle stem cells lose their ability to change into different cell types after being grown for a long time.
1 citations
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August 2024 in “Transgenic Research” Activated β-catenin affects hair growth and skin thickness, and changes are reversible.
1 citations
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December 2016 in “Trichology and cosmetology:” Panax ginseng might help with hair growth and has fewer side effects than synthetic treatments.
September 2023 in “Stem cell reviews and reports” Scientists found a new, less invasive way to get stem cells from horse hair for veterinary medicine.
451 citations
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March 2005 in “Endocrine Reviews” The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.
137 citations
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September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
53 citations
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March 2014 in “Growth Hormone & IGF Research” IGF-1 injections help mice grow more hair by increasing cell growth and blocking a hair growth inhibitor.
37 citations
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August 2014 in “Journal of experimental botany” A gene in Arabidopsis thaliana, AtPRPL1, affects root hair length but not cell wall composition.
21 citations
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July 2006 in “Veterinary dermatology” CD34 marks potential stem cells in dog hair follicles.
4 citations
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July 2012 in “Genesis” The Megsin-Cre transgene is a new tool for genetic manipulation in the skin and upper digestive tract.
91 citations
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July 2010 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
6 citations
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January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
80 citations
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May 2011 in “Nature Cell Biology” New methods have greatly improved our understanding of stem cell behavior and roles in the body.
71 citations
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January 2015 in “Journal of molecular cell biology/Journal of Molecular Cell Biology” mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
67 citations
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December 2009 in “Stem Cells” β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.
66 citations
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August 1999 in “The Journal of Clinical Endocrinology & Metabolism” Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
61 citations
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September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
15 citations
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January 2015 in “Skin Pharmacology and Physiology” Parathyroid hormones are important for hair growth, but their use in treating hair loss from chemotherapy is still uncertain.
14 citations
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October 2000 in “Genomics” Rat dermal papilla cells have unique genes crucial for hair growth.
7 citations
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November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
6 citations
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January 2016 in “Journal of Stem Cell Research & Therapy” Notch1 signaling is crucial for improving wound healing and skin regeneration by affecting stem cell behavior.
2 citations
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November 2024 in “GSC Biological and Pharmaceutical Sciences” Serums effectively improve skin and hair issues, boosting confidence when used correctly.