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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Finasteride reduces hair loss and treats BPH without major hormone changes, but may cause sexual dysfunction.

5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

Pueraria mirifica extract may help treat benign prostatic hyperplasia.

Finasteride affects prostate weights and pituitary activity differently with age.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Taking oral testosterone with or without dutasteride increases testosterone levels and could be an effective treatment for low testosterone.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.

Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Male hormones affect oil-producing skin cells differently based on their body location, and the drug spironolactone can reduce these effects.

New compounds may soon be tested to treat excessive hair growth in women.

Avicequinone C, a compound found in the Avicennia marina plant, can reduce hair loss by inhibiting a hormone linked to androgenic alopecia.

A new plant extract from Avicennia marina could potentially be used to treat common hair loss.

Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.

Finasteride helps treat hair loss by blocking enzyme activity.