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Mitochondrial problems in diabetic nerve damage might cause pain by lowering the production of certain nerve-related steroids.

Neurosteroids in the brain can increase or decrease seizure risk in mice.

Finasteride can cause serious mental health issues, so it's advised to avoid it for hair loss.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

Finasteride treats baldness but may cause lasting sexual side effects.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Rodent models of PCOS show some hormone changes similar to humans, but also have key differences.

Pregnenolone might help manage movement issues caused by Parkinson's disease treatment without reducing the medicine's effectiveness.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Stress increases neurosteroids that help prevent seizures.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Isoallopregnanolone may be a safe and effective treatment for reducing tics in a mouse model of Tourette syndrome.

Finasteride reduces movement issues in Parkinson's disease rats.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Finasteride reduces response to stress and rewards, affecting behavior and mental health.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

Midazolam impairs learning and memory by increasing neurosteroids through specific receptor activation.

Neurosteroids show promise for treating epilepsy and more research is needed.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.