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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.

Progesterone and related compounds may help control seizures linked to the menstrual cycle but have limitations that need addressing.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Alcohol in teen years leads to more adult drinking, finasteride doesn't help.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride doesn't affect ovulation in normal women.

Finasteride and dutasteride may help prevent hair loss but could cause side effects like sexual dysfunction and psychological issues.

Consider benefits and risks of new alopecia treatments for safety.

Finasteride may increase depression by reducing brain cell growth.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Estrogen and androgen signals control synaptic changes in rat brains.

Finasteride blocks progesterone's effect on absence seizures in rats.

Some common medications can harm male fertility, but many effects can be reversed.

Finasteride for hair loss may cause lasting sexual, genitourinary, mental, and anti-androgenic side effects in young men.

Dutasteride is more effective and better tolerated than finasteride for hair loss treatment.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

A brain-produced steroid causes increased scratching in mice with a skin condition similar to eczema.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.