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Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Finasteride effectively blocks enzyme causing male pattern baldness.

The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.

Minoxidil boosts enzymes that help hair growth.

Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.

Finasteride causes abnormal growth in male mice cells at high doses.

Using 5α-reductase inhibitors for hair loss may increase the risk of dry eye disease.

Using 5α-reductase inhibitors for hair loss can cause lasting sexual, physical, mental, and vascular health issues in men, even after stopping the medication.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Finasteride effectively treats male hair loss, improving growth and density.

Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.

A higher testosterone/dihydrotestosterone ratio in PCOS patients may indicate worse metabolic health.

Finasteride and minoxidil together promote hair growth better than either alone.

Four-amino acid part makes enzyme sensitive to finasteride.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Finasteride negatively affects fish reproduction and gonadal development.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Jute leaves may help reduce DHT levels, potentially aiding in conditions like hair loss and prostate issues.

High testosterone to epitestosterone ratio in hair could predict male-pattern baldness.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Long-term use of dutasteride can cause permanent erectile dysfunction in rats.

Finasteride doesn't harm bone density in older men with BPH.

Certain drugs change freshwater snail shells to a "banana" shape.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.