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Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

5α-reductase enzyme affects hormone levels, influencing conditions like acne and hair loss.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Scientists made a carbon-14 labeled version of a drug with a 48% yield and over 99% purity.

sPLA2-IIA increases growth in hair follicle stem cells and cancer cells, suggesting it could be targeted for hair growth and cancer treatment.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

The equine epididymis mainly uses type 1 5α-reductase, and both finasteride and dutasteride can inhibit its activity.

Phytosterols may help manage prostate issues but are less effective than synthetic drugs.

Different forms of FGF5 either promote or inhibit hair growth.

The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Serotonin helps wounds heal faster.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

A new compound may treat benign prostatic hyperplasia better than finasteride.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Activating ALDH2 can boost hair growth.

Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

A protein made in a plant stopped hair growth in mice.

Activating Tgr5 may help treat hair loss and bone loss.

A new compound effectively inhibits human 5α-reductase 1.

Targeting FGF5 could help treat prostate cancer.