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Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

Testosterone reduces knee movement, while flutamide and finasteride increase it.

Letrozole reduces seizures but not brain damage in mice.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Blocking prolactin increases the activity of secondary hair follicles in cashmere goats.

mTORC2 is crucial for healthy skin barrier by regulating lipids and filaggrin.

5α-reductase inhibitors may reduce male fertility and could be used for male contraception.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Finasteride and dutasteride effectively treat hair loss in men and women, but may cause side effects like low libido and depression.

Overexpression of COX-2 causes early hair loss in mice, but can be prevented with a COX-2 inhibitor.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.

Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.

5-alpha reductase inhibitors help with benign prostatic hyperplasia but don't cure it, and more research is needed.

Finasteride may cause sexual dysfunction by reducing epinephrine levels.

Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

Finasteride boosts immune cells that suppress T-cells, possibly helping with immune disorders but may increase cancer risk.

Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

The ACTH/MC2R system is crucial for controlling hair growth cycles in mice.

MK-386 lowers DHT in blood and skin but not in semen.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.

Men taking 5α-reductase inhibitors for enlarged prostate have a higher chance of experiencing reduced sexual desire and erectile dysfunction.

EETs can delay seizures by affecting GABA activity, offering potential new treatments for seizures.