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Adding soybean oil to Nonomuraea dietziae increases production of a beneficial compound by improving metabolism and enzyme systems.

A fungal enzyme was used to make compounds more soluble, aiding drug discovery and crop protection.

Sebocytes play a key role in controlling androgen levels in human skin.

A new method to make finasteride for hair loss treatment was developed.

Lower MC2R expression may contribute to alopecia areata.

New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.

The new method for making finasteride is cheaper and gives a higher yield.

The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.

High levels of ODC and a mutant Ha-ras gene cause tumors in mice.

Csdc2 helps hair growth in cashmere goats by regulating specific genes.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Ovarian and stress hormones can change GABA A receptors through neurosteroids.

ALKBH5 helps wounds heal faster by stabilizing PELI2 mRNA.

Neurosteroids regulate synaptic inhibition in the spinal cord and may help manage spinal pain.

The ACTH/MC2R system is crucial for controlling hair growth cycles in mice.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Very-long-chain acyl-CoA synthetases and fatty acid transport proteins play key roles in fatty acid metabolism and lipid processing in different tissues.

Both drugs lower DHT levels, with GI198745 being more effective.

Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.

Taking 5α-reductase inhibitors with prednisolone can worsen its negative effects on metabolism.

Baldness in men with prostate cancer is linked to higher levels of certain sex hormones, but chest hair density is not.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.