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LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

Elf5 controls skin cell growth and development, making it a potential target for skin treatments.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Targeting FGF5 could help treat prostate cancer.

A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.

The human type II 5α-reductase gene, linked to certain male health conditions, has a specific structure and low similarity to other related genes.

Finasteride safely treats enlarged prostate and male-pattern baldness.

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

Hexahydrobenzo[f]quinolines are effective at blocking the enzyme 5α-reductase.

Methylated gene parts may cause finasteride-resistance in some enlarged prostate patients.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

miR‑339‑5p can slow down hair follicle stem cell differentiation by targeting DLX5.

5α-Reductase inhibitors don't cause depression.

Glucocorticoids reduce fat production in liver cells, while androgens increase it in females; manipulating certain enzymes can influence these effects.

Plerixafor may help treat pigmentation disorders by promoting skin repigmentation.

FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.

Some men's prostate tissues have low enzyme levels due to genetic changes, possibly affecting treatment for prostate enlargement.

5ARIs lower PSA levels, but other tests are needed to avoid missing aggressive prostate cancer.

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

5-Alpha reductase inhibitors help treat enlarged prostate but may cause sexual side effects.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

PRMT5 inhibitors effectively fight adenoid cystic carcinoma in salivary glands.

5alpha-reductase 2 is crucial for proper male brain development and sexual differentiation.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

Neuroactive steroids and the enzyme 5α-reductase might be involved in the development of Tourette's syndrome.