2 citations
,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
April 2017 in “Actas urológicas españolas” 5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
July 2022 in “L Endocrinologo” A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.
24 citations
,
October 1994 in “Fertility and Sterility” People with hair loss may have different levels of certain hormones due to changes in hormone processing.
29 citations
,
July 2009 in “BJU international” Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
3 citations
,
September 2016 in “Natural Product Communications” Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.
February 2024 in “The Journal of Sexual Medicine” 5-α reductase inhibitors do not significantly affect male reproductive function but may reduce semen volume.
18 citations
,
April 2011 in “Neuropharmacology” 11β-Hydroxylase inhibitors help prevent seizures in mice by boosting natural neurosteroid production.
January 2008 in “Journal of Medicinal Chemistry” Finasteride may cause sexual and psychological side effects by affecting an enzyme related to epinephrine.
61 citations
,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” January 2004 in “DOAJ (DOAJ: Directory of Open Access Journals)” Men with androgenetic alopecia do not have elevated DHEA-S levels.
20 citations
,
April 2009 in “Fertility and Sterility” January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” The method is quick and effective for testing steroid 5 alpha-reductase inhibitors.
7 citations
,
December 1971 in “European Journal of Endocrinology” Human hair follicles can process steroid hormones like DHEA.
February 2016 in “PubMed” Properly administered testosterone therapy is safe and effective but often not covered by insurance.
The oral testosterone effectively increased testosterone levels and reduced SHBG, showing promise for treating testosterone deficiency.
15 citations
,
January 2017 in “Advances in Experimental Medicine and Biology” 5α-Reductase inhibitors can negatively affect male sexual function and, in some cases, significantly reduce sperm count, but these effects may be reversible.
November 2007 in “Neuro-chirurgie/Neurochirurgie” Cyproterone acetate is a safe treatment that causes mild feminizing effects and is more effective with added estrogens.
May 2026 in “Mendeley Data” April 2026 in “Mendeley Data” May 2026 in “Mendeley Data”
August 1993 in “Journal of Dermatological Science” Testosterone metabolism in balding scalp cells may not be the main cause of hair loss.
186 citations
,
February 1980 in “Clinical Endocrinology” During puberty, hormone levels rise, with early increases in some steroids and most menstrual cycles becoming regular by six years after menarche.
14 citations
,
November 1982 in “British Journal of Dermatology” Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
2 citations
,
May 2012 in “Indian drugs” Finasteride, a hair loss treatment, works better and is more stable when delivered through specially prepared gels, leading to increased hair growth.
46 citations
,
July 2010 in “Advances in Therapy” SPET-085 effectively inhibits an enzyme linked to prostate issues, similar to finasteride.
January 2012 in “ProQuest LLC eBooks” Changes in early neurosteroid levels can affect adult learning and anxiety.
October 2025 in “Journal of the Endocrine Society” Anastrozole can cause increased testosterone, leading to symptoms like hair growth and thinning.
94 citations
,
August 2002 in “Experimental Dermatology” 17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.