101 citations
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January 1985 in “British Journal of Dermatology” Spironolactone is effective for treating acne, hirsutism, and androgenic alopecia in women with few side effects.
97 citations
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December 2011 in “New England Journal of Medicine” The FDA did not approve certain drugs for prostate cancer prevention due to concerns about their effectiveness and potential risks.
95 citations
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February 2018 in “Dermatology and Therapy” Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.
95 citations
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September 1979 in “Acta Paediatrica” Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.
94 citations
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April 2018 in “Nature Genetics” New genetic locations explain much of hair color variation in Europeans.
91 citations
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May 2003 in “PubMed” Neuroactive steroids affect cocaine's rewarding effects through the sigma1 receptor.
90 citations
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November 2014 in “Journal of Biomedical Optics” Silver nanoparticles can penetrate porcine skin up to about 15.6 μm, possibly through hair follicles.
90 citations
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August 2002 in “European journal of endocrinology” Metformin improves hair growth and menstrual frequency in women with PCOS and hirsutism.
90 citations
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January 2002 in “Dermatology” Kenogen is a resting phase in hair follicles that may contribute to baldness, especially in androgenetic alopecia.
88 citations
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December 2012 in “Journal of The European Academy of Dermatology and Venereology” Injecting CD34+ cell-containing platelet-rich plasma into the scalp can improve hair count and thickness in people with pattern hair loss.
85 citations
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January 2014 in “Hormone Research in Paediatrics” Hair cortisol levels in children increase with age but are not affected by gender, puberty, or hair care.
85 citations
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April 2004 in “Thyroid” Thyroid problems can negatively affect women's reproductive health and pregnancy, and can cause symptoms like fatigue and depression, but not all women with these symptoms need treatment.
84 citations
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January 1987 in “The Pediatric Infectious Disease Journal” Griseofulvin is more effective than ketoconazole for treating tinea capitis in children.
82 citations
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January 1994 in “Skin Pharmacology and Physiology” Hair follicles and glands significantly increase steroid absorption in skin.
80 citations
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February 2021 in “Cureus” Many COVID-19 survivors continue to experience symptoms like fatigue and concentration problems after recovery, possibly needing rehabilitation.
76 citations
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September 1992 in “Endocrinology” The human type II 5α-reductase gene has a specific structure important for understanding certain medical conditions.
74 citations
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April 2002 in “PubMed” Both oral contraceptives reduced acne effectively and had similar positive effects on skin oiliness and hair growth.
72 citations
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January 2012 in “Annals of Dermatology” IGF-I promotes hair growth by keeping hair follicles in the growth phase longer.
69 citations
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April 1998 in “Journal of The American Academy of Dermatology” Single hair grafting is effective for treating small, localized patches of vitiligo.
67 citations
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January 2007 in “Environmental health perspectives” A woman's health issues were caused by arsenic poisoning from kelp supplements.
66 citations
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November 2001 in “European journal of endocrinology” Low SHBG and high FAI, FT, and DHEAS levels are effective in identifying PCOS.
59 citations
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January 2003 in “Phytomedicine” Fennel extract cream can reduce hair thickness in people with excessive hair growth.
57 citations
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August 2020 in “Journal of the American Geriatrics Society” Most adults over 70 have skin diseases needing treatment, with men more affected than women.
56 citations
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July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
54 citations
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March 2012 in “International Journal of Andrology” Prenatal pesticide exposure may cause earlier breast development in girls.
54 citations
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May 1998 in “Urology” Men with enlarged prostates often have more severe baldness.
52 citations
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May 2019 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil effectively improves male hair loss with mild side effects.
52 citations
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March 2015 in “Tissue Engineering Part C Methods” 3D images of skin show collagen is evenly spread, but elastic fibers are fewer near hair follicles.
52 citations
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February 2003 in “Archives of dermatology” 9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.
51 citations
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November 2011 in “British Journal of Dermatology” A gene called HDAC9 might be a new factor in male-pattern baldness.