1 citations
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January 2022 in “European Journal of Pharmacology” Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.
May 2025 in “Journal of the European Academy of Dermatology and Venereology” Etrasimod is safe but not effective for severe alopecia areata, though it may help milder cases.
PMEE may help reverse greying hair by boosting melanin production.
13 citations
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September 2011 in “International Urology and Nephrology” 1 citations
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February 1991 in “Journal of Biological Chemistry” November 2025 in “Journal of Investigative Dermatology” The study investigates the effects of N,N-Dimethylglycine sodium salt (DMG-Na) on human skin cells, revealing its potential as a multifaceted skin treatment. DMG-Na promotes cell proliferation, migration, and VEGF release in HaCaT keratinocytes, while exhibiting anti-inflammatory and antioxidant properties in models of skin diseases. It increases intracellular calcium and nitric oxide production in HDMECs, enhancing skin blood flow. In dermal papilla cells, DMG-Na reverses senescence-associated changes, indicating anti-aging benefits. A pilot study with a 1% DMG-Na gel confirmed its vasodilatory effects. These findings suggest DMG-Na could treat various skin conditions, including hair loss, with further clinical studies underway to assess its broader therapeutic potential.
26 citations
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October 2011 in “International Journal of Biological Macromolecules” Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.
14 citations
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May 2019 in “Human gene therapy” MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
36 citations
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October 2019 in “Cell Proliferation” Tryptanthrin effectively suppresses non-melanoma skin cancer and is safe for normal skin.
20 citations
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September 2005 in “Endocrinology” Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
1 citations
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October 2020 in “Annales pharmaceutiques françaises” The document concludes that a new method for measuring Minoxidil and Finasteride in hair regrowth solution is better because it considers separation theory and the properties of the ingredients. The mix of Methanol and water and the pH level greatly impact the measurement time and clarity.
5 citations
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January 2018 in “Skin appendage disorders” Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
November 2005 in “CRC Press eBooks” SEPA 0009 is a promising and safe skin penetration enhancer for topical use.
December 2024 in “Journal of Cosmetic Dermatology” ME1 and PPAR signaling may influence hair loss in androgenetic alopecia.
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
9 citations
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January 1999 in “Journal of Liquid Chromatography & Related Technologies” Best results found using acetonitrile, water, and trifluoroacetic acid or methanol mixture.
January 2012 in “Anales (Reial Acadèmia de Medicina de la Comunitat Valenciana)” SRD5A2 enzyme expression varies in benign prostates and can be influenced by inflammation, affecting treatment options.
3 citations
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June 2018 in “Bioorganic & medicinal chemistry” Compounds 4, 4b, and 4c effectively inhibit an enzyme linked to testosterone conversion without significant toxicity.
April 2008 in “Annals of General Psychiatry” Social isolation changes brain receptors and makes ethanol more impactful.
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November 2025 in “Clinical Chemistry and Laboratory Medicine (CCLM)” A new method accurately measures DHEAS in blood, improving on current tests.
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June 2003 in “PubMed” The two finasteride formulations are bioequivalent.
1 citations
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December 2022 in “Biomolecules & therapeutics” Minoxidil may help reduce aging effects in brain cells.
April 2020 in “The FASEB Journal” Finasteride may cause lasting sexual issues by altering specific genes in human cells.
January 2025 in “BioMed Research International” Targeting DNA methylation can help treat skin disorders and cancers.
34 citations
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October 1975 in “Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis” Finasteride affects prostate development differently in male and female Mongolian gerbils.
1 citations
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June 1959 in “A M A Archives of Dermatology” Methyl prednisolone helps most patients with alopecia universalis regrow hair.
249 citations
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April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
5 citations
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January 1985 in “Annals of Nutrition and Metabolism” Methionine intake changes tooth germ development in newborn rats.
March 2014 in “Journal of The American Academy of Dermatology” Mycophenolic acid may help hair grow by activating pathways important for hair growth.