May 2017 in “InTech eBooks” Some hair loss disorders cause permanent loss due to scarring, and treatments like steroids don't always work well.
The chapter explains that there are many genetic skin disorders affecting skin cell formation, including both common and rare types.
January 2014 in “Journal of Pigmentary Disorders” Women's hair gets thinner and grayer as they age, with treatments available for hair loss and graying.
June 2004 in “Dermatologic Surgery” Dr. Walter P. Unger suggests that copying a person's natural hair direction and angle during transplants leads to a more natural and fuller appearance.
5 citations
,
January 2012 in “International journal of trichology” A 2-year-old boy had no hair and unusual organ placement, and it's unclear if it's genetic or coincidental.
January 2011 in “Journal of Human Genetics” A Japanese patient with a rare genetic disorder had a less severe case than others, suggesting other factors may affect symptoms.
121 citations
,
December 2001 in “American Journal of Dermatopathology” TB and BCC tumors show similar follicular differentiation patterns.
82 citations
,
March 2012 in “Development” Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.
68 citations
,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
65 citations
,
November 2016 in “Journal of The American Academy of Dermatology” The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.
62 citations
,
August 2018 in “Frontiers in Endocrinology” Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
48 citations
,
March 1997 in “Veterinary Dermatology” Some cats with sudden hair loss and tiredness might have cancer-related alopecia.
44 citations
,
April 2017 in “Genes & development” Scientists found cells in hair that are key for growth and color.
43 citations
,
July 2014 in “Experimental Dermatology” Hair follicles can help wounds heal faster and this knowledge could be used to treat chronic skin ulcers, with a potential use of a special stem cell hydrogel to enhance healing.
37 citations
,
June 2011 in “Journal of The American Academy of Dermatology” Loss of sebaceous glands and inflammation may contribute to the development of scarring alopecia.
35 citations
,
January 2011 in “Journal of Biological Chemistry” sPLA2-X is crucial for normal hair growth and follicle health.
29 citations
,
September 2014 in “American Journal of Dermatopathology” Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
23 citations
,
November 2018 in “Journal of the European Academy of Dermatology and Venereology” The study concluded that severity of Frontal fibrosing alopecia is not linked to how long someone has it, can start before menopause, and eyebrow loss may be an early sign.
23 citations
,
September 2014 in “Journal of The American Academy of Dermatology” The robotic hair restoration device had a high success rate and was faster than manual methods for Korean patients.
18 citations
,
October 2012 in “Dermatologic Clinics” Early diagnosis and aggressive treatment are key for managing rare scalp disorders that cause permanent hair loss.
18 citations
,
March 2004 in “Clinics in Dermatology” Lupus can cause hair loss and nail changes, with treatments available for both.
16 citations
,
February 2018 in “Journal of The American Academy of Dermatology” Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.
13 citations
,
May 2004 in “Dermatologic Surgery” The paper concludes that copying the natural direction and angle of hair in transplants is key for a natural look and doesn't harm hair survival.
12 citations
,
January 2006 in “Aesthetic Plastic Surgery” Micrografts can effectively restore pubic hair, and using the right technique is crucial for natural-looking results.
9 citations
,
January 2017 in “Virchows Archiv” LGR5 and LGR6 are expressed differently in various skin tumors, which may offer clues about their origins.
5 citations
,
September 2012 in “Dermatology Online Journal” Follicular Unit Extraction (FUE) hair transplant is less invasive, leaves no scars, and has quicker recovery times, but it's more time-consuming and challenging. Automation helps speed up the process and improve graft survival, reducing the need for traditional strip surgery.
4 citations
,
January 2020 in “Journal of Cutaneous and Aesthetic Surgery” Keloid scars can form after hair transplant surgery and should be prevented and treated early.
4 citations
,
January 2014 in “Indian dermatology online journal” Monilethrix is a genetic hair disorder causing fragile, beaded hair with no effective treatment.
4 citations
,
February 2008 in “Dermatologic Surgery” Hair transplant surgery successfully restored a woman's pubic hair, improving her appearance and satisfaction.
3 citations
,
April 2018 in “Therapeutic Delivery” Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.