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Genetic Alteration of Cyclic Adenosine 3',5'-Monophosphate-Dependent Protein Kinase Subunit Expression Affects Calcium Currents and Beta-Endorphin Release in AtT-20 Clonal Pituitary Cells

research Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.

August 1994 in “Molecular Endocrinology”

Changing protein kinase levels in pituitary cells affects calcium flow and beta-endorphin release.

research TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network

February 2026 in “Advanced Science”

TTNPB helps turn stem cells into neural stem cells, improving depression-like behaviors in rats.

research Induction of dark keratinocytes by 12-O-tetradecanoyl-phorbol-13-acetate and mezerein as an indicator of tumor-promoting efficiency

77 citations , January 1980 in “Carcinogenesis”

TPA is about 50 times more effective at promoting tumors than MZ.

research Synchronizing actin and microtubules for axonal branching

3 citations , August 2012 in “Nature Cell Biology”

Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.

The Compatibility of Bacillus Thuringiensis Cry Protein-Solubilizing Buffers with the Droplet Feeding Method in Fall Armyworm Larvae

research The compatibility of Bacillus thuringiensis Cry protein-solubilizing buffers with the droplet feeding method in fall armyworm larvae

August 2019 in “Journal of Invertebrate Pathology”

Thymosin beta 4 protects cells from damage by blocking a harmful microRNA and boosting a protective gene.

research Carbobenzoxy-capped Phe-Lys(BODIPY TMR-X-acyloxymethyl ketone(QSY7)

May 2010 in “Europe PMC (PubMed Central)”

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

research Targeted Inactivation of Gh/Tissue Transglutaminase II

288 citations , January 2001 in “Journal of Biological Chemistry”

Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.

Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model

research 014 Tyrosine Kinase 2 Inhibition Ameliorates the Phenotype of Lesional Alopecia Areata Scalp Skin Ex Vivo, and Reverses the Induction of Human Alopecia Areata in a Humanized Mouse Model

November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology”

TYK2 inhibition may help treat alopecia areata by promoting hair growth and reducing immune response.

research KIF18B is a cell-type specific regulator of spindle orientation in the epidermis

June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)”

KIF18B is important for correctly positioning cell division machinery in skin cells, affecting hair follicle development.

research Targeted expression of spermidine/spermine N1-acetyltransferase increases susceptibility to chemically induced skin carcinogenesis

54 citations , February 2002 in “Carcinogenesis”

Increasing SSAT makes skin more prone to cancer.

research Androgens Regulate Tau Phosphorylation Through Phosphatidylinositol 3-Kinase–Protein Kinase B–Glycogen Synthase Kinase 3β Signaling

14 citations , June 2022 in “Neuroscience”

The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function

72 citations , January 2003 in “American Journal of Pathology”

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

research Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity

November 2023 in “Advanced Science”

A specific hair protein variant increases the spread of breast cancer and is linked to worse survival rates.

research Direct evidence supporting the existence of a helical dislocation in protofilament packing in the intermediate filaments of oxidized trichocyte keratin

3 citations , September 2018 in “Journal of Structural Biology”

Oxidized trichocyte keratin has a helical dislocation in its structure.

research Decision letter: NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures

December 2015

NuMA-microtubule interactions are vital for proper skin structure formation and function.

research A mutation in MAP2 is associated with prenatal hair follicle density

11 citations , November 2019 in “The FASEB Journal”

A mutation in the MAP2 gene causes reduced hair follicle density, leading to hairlessness.

research Purification and Calcium Dependence of Transglutaminases from Sheep Hair Follicles

7 citations , January 1997 in “Bioscience Biotechnology and Biochemistry”

Sheep hair follicle transglutaminases are calcium-dependent.

research Apoptosis and keratin intermediate filaments

180 citations , April 2002 in “Cell Death and Differentiation”

research P5 Assembly of hair keratins in thansfected cultured cells

April 1996 in “Journal of Dermatological Science”

The TFIID Subunit TAF4 Regulates Keratinocyte Proliferation and Has Cell-Autonomous and Non-Cell-Autonomous Tumor Suppressor Activity in Mouse Epidermis

research The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

28 citations , July 2007 in “Development”

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

research Hair follicle targeting via gelatin coated transferosomes loaded with tofacitinib citrate for enhanced treatment of alopecia areata: Clinical evaluation of alopecia areata patients

January 2025 in “International Journal of Pharmaceutics”

The treatment showed significant hair regrowth in alopecia areata patients without side effects.

research Neurotrophin-4 modulates the mechanotransducer Cav3.2 T-type calcium current in mice down-hair neurons

11 citations , September 2011 in “Biochemical journal”

Neurotrophin-4 increases calcium current in specific mouse neurons through the PI3K pathway.

research Relationships between hair-follicle afferent terminations and glutamic acid decar☐ylase-containing boutons in the cat's spinal cord

46 citations , April 1987 in “Brain Research”

Hair-follicle nerves in cats' spinal cords can be inhibited by GABA-related connections.

research Coordination of force-generating actin-based modules stabilizes and remodels membranes in vivo

3 citations , August 2024 in “The Journal of Cell Biology”

Actin filaments help stabilize and reshape cell membranes.

research Trichotillomania treated with n-acetylcysteine

3 citations , May 2018 in “Psychiatry and Clinical Psychopharmacology”

N-acetylcysteine may help treat trichotillomania.

research Faculty Opinions recommendation of Expression of truncated latent TGF-beta-binding protein modulates TGF-beta signaling.

May 2005 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”

Truncated LTBP-1 disrupts TGF-beta signaling, affecting hair growth.

research Intramembrane Proteolysis of Astrotactins

8 citations , January 2017 in “Journal of Biological Chemistry”

Astrotactin-2 is cleaved in a specific way that helps understand its maturation.

research Overexpression of spermidine/spermine N1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue

13 citations , March 1999 in “Biochemical Journal”

Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.

research Synthesis of a new amino acid derivative with long‐lasting hair shape control effects and elucidation of its mechanisms

February 2025 in “International Journal of Cosmetic Science”

A new amino acid derivative, ATS, improves hair texture and moisture, making it easier to straighten curly hair.

research 516 Dynein is involved in the movement, distribution, acidity, and transfer of melanosomes

November 2022 in “Journal of Investigative Dermatology”

Dynlt3 is important for melanosome transport and skin coloration.

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