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2-DG reduces seizures by enhancing brain inhibition through specific receptor activation.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Inhibiting certain enzymes made female rats more sensitive to low-level pain.

A new method was developed to measure and assess the activity and inhibition of the enzyme steroid 5α-reductase.

2-Hydroxy-1,4-naphthoquinone is a strong 5α-reductase inhibitor.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Smaller substituents at C-17 enhance the inhibitory activity of progesterone derivatives on 5alpha-reductase.

Adiantum capillus extract reduces pain and swelling in animals.

Isotretinoin shows promise as a treatment for Chagas disease by effectively inhibiting key transporters in the parasite.

The new compound is a promising, less toxic alternative to finasteride for treating prostate issues.

14,15-EET may help reduce poststroke pain by affecting certain brain proteins.

Disruption of glycinergic circuits increases pain sensitivity, suggesting new pain treatment options.

Near-infrared probes can safely and effectively image cysteine protease activity for disease diagnosis.

Finasteride reduces certain behaviors caused by D1-like receptor agonists but not by D2-like receptor agonists in mice.

Betulinic acid can help treat hepatitis C by stopping virus replication.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.

Compounds from turmeric and bitter show strong potential as antiviral agents against the influenza A virus.

The compound GD-23 may reduce anxiety like diazepam by targeting the TSPO receptor.

Three specific 4-azasteroid-2-oximes showed strong enzyme inhibition, but less than finasteride.

A reliable method was developed to measure aristolochic acid-I in rat blood.

HDAC inhibitors help brain cells grow and improve brain function.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.

Bruguiera gymnorhiza leaf extracts show potential for developing anti-inflammatory drugs.

Chemotherapy significantly lowers Inhibin A levels in breast cancer patients.

Ethanol blocks memory formation in rats by enhancing certain brain chemicals.

Chloroquine and cinchonine relax rat blood vessels by affecting calcium channels, with chloroquine needing caution in heart patients.