21 citations
,
June 1991 in “Journal of Inherited Metabolic Disease” Selenium deficiency caused symptoms in a child, which improved with selenium supplements.
22 citations
,
September 2008 in “Brain & development” Biotin supplements increased biotin levels but did not significantly prevent hair loss in rats on valproic acid.
September 2009 in “European journal of paediatric neurology” Biotin supplements did not significantly reduce hair loss in rats on valproic acid.
2 citations
,
August 2020 in “JCRPE” A girl with Denys-Drash syndrome was misdiagnosed due to biotin affecting her hormone test results.
6 citations
,
January 2016 in “Pediatrics international” Japanese infants fed hydrolysate formula may have low biotin levels.
18 citations
,
June 2016 in “Clinical and Experimental Dermatology” Increasing isoleucine intake improved skin and health issues in an infant with maple syrup urine disease.
4 citations
,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
September 2024 in “Journal of Clinical and Translational Endocrinology Case Reports” Biotin can interfere with lab tests, causing misdiagnosis.
10 citations
,
October 2017 in “Pediatric neurology” Biotin and acetazolamide improved hair and nail growth, mental function, and reduced headaches in a child with autism.
1 citations
,
February 2022 in “Journal of the American Academy of Dermatology” Taking biotin supplements can be risky and often lacks evidence of effectiveness for skin, hair, and nail issues.
August 2023 in “Dermatology reports” A baby with maple syrup urine disease improved from skin problems by adjusting his diet to correct amino acid levels.
2 citations
,
December 2014 Low biotin intake during pregnancy can affect biotin transport in mothers and fetuses.
9 citations
,
February 1984 in “Zentralblatt für Veterinärmedizin Reihe A” Biotin is essential for healthy skin and claws in pigs.
2 citations
,
October 2016 in “OPAL (Open@LaTrobe) (La Trobe University)” The Swedish neonatal screening program effectively detects PKU, galactosaemia, and biotinidase deficiency with low false positives.
53 citations
,
March 2003 in “Journal of Investigative Dermatology” Human skin cells have a high-affinity system for biotin transport, crucial for skin health.
55 citations
,
November 2019 in “Cellular and Molecular Gastroenterology and Hepatology” Biotin may help treat inflammatory bowel disease by reducing inflammation and improving gut health.
Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.
13 citations
,
January 2019 in “Journal of the American Academy of Dermatology” Most people using biotin don't see skin improvements, and it may affect lab tests, so doctors shouldn't suggest it without confirming a deficiency.
21 citations
,
January 1945 in “Journal of Nutrition” Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.
November 2022 in “Journal of the Endocrine Society” Taking biotin can lead to incorrect low results in free testosterone tests.
2 citations
,
January 1989 Tay syndrome is a unique genetic disorder causing skin, hair, and developmental issues.
43 citations
,
October 1955 in “The journal of nutrition/The Journal of nutrition” Germ-free rats need biotin for growth and have different vitamin metabolism compared to regular rats.
September 2022 in “Farmacja Polska” Biotin is important for health, but taking extra usually doesn't help unless you're deficient.
1 citations
,
June 2022 in “Tidsskrift for Den norske legeforening” A young boy's uncombable hair is due to a rare genetic condition that usually improves over time.
5 citations
,
May 2019 in “Cureus” Taking biotin supplements can cause incorrect thyroid test results, leading to wrong diagnoses.
21 citations
,
June 2011 in “Journal of child neurology” Valproic acid and carbamazepine do not change biotin or biotinidase levels but may lower zinc levels, still within normal range.
Taking too much biotin can mess up blood test results, which might lead to wrong diagnoses and treatments.
11 citations
,
September 2010 in “PubMed” Zinc and biotin supplements are needed after certain surgeries to prevent hair loss and other issues.
August 2022 in “Journal of the American Academy of Dermatology” The authors agree they didn't discuss the risks of too much micronutrients and value the focus on biotin deficiency signs and treatment effectiveness.
25 citations
,
December 2005 in “Molecular Genetics and Metabolism” Taking riboflavin and eating less lysine can help some people with a specific genetic disorder avoid brain damage.