January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Auxin helps root hairs grow in high phosphate by affecting ROS and involving RSL2 and RSL4.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
January 2016 in “Springer eBooks” The document concludes that there are various causes and treatments for hair loss, with hair transplantation being a notable option.
November 2014 in “PharmaTutor” Finasteride may help postmenopausal women with hair loss but is not effective for all and should be used cautiously in premenopausal women.
September 2013 in “Molecular Biology” The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
August 2013 in “Nature Reviews Drug Discovery” New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
August 2013 in “Nature Reviews Drug Discovery” New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
August 2013 in “Nature Reviews Drug Discovery” New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
April 2013 in “Developmental Cell” Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.
June 2006 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Melatonin may help reduce the needed dose of prednisolone and improve hair growth in alopecia areata patients.
June 2022 in “International journal of drug delivery technology” Convolvulus arvensis ethanolic extract can potentially promote hair growth and reduce hair loss.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
June 2020 in “Aesthetic Surgery Journal” Estradiol-rich plasma can increase hair density faster and more effectively in male pattern baldness treatment than regular plasma.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
January 2007 in “Revista del Centro Dermatológico Pascua” Hair loss in women, often not related to male hormones, increases with age and can cause significant emotional distress.
81 citations
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September 2005 in “The American journal of pathology” Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.
1533 citations
,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
1415 citations
,
October 2007 in “European Journal of Epidemiology” The Rotterdam Study investigates diseases in older adults and has produced many research findings.
788 citations
,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
759 citations
,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
667 citations
,
May 2008 in “Genes & Development” Histone demethylases can change gene expression and may be linked to diseases like cancer.
610 citations
,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
556 citations
,
September 2008 in “Genes & Development” Wnt signaling is vital for cell growth, development, and cancer research.
474 citations
,
January 2012 in “Chemistry & biology” Proteasome inhibitors are promising treatments for various cancers, autoimmune diseases, and other conditions.
471 citations
,
October 2012 in “Cellular and Molecular Life Sciences” Understanding developmental pathways can improve wound healing treatments.
403 citations
,
December 2018 in “Cell stem cell” Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
375 citations
,
July 2006 in “Journal of Investigative Dermatology” Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
354 citations
,
February 2011 in “Genes & Development” EZH1 and EZH2 are crucial for healthy hair growth and skin repair.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
306 citations
,
April 2019 in “International Journal of Molecular Sciences” The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.