research Stem cells in tissues, organoids, and cancers
Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.
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research Tooth Regeneration: Insights from Tooth Development and Spatial-Temporal Control of Bioactive Drug Release
Tooth regeneration could become possible by controlling how and when bioactive factors are released.
research Calcium regulation of stem cells
Calcium is important for stem cell function and maintenance, especially in blood and skin cells.
research Exploring the Therapeutic Potential of TGF-β Inhibitors for Liver Fibrosis: Targeting Multiple Signaling Pathways
TGF-β inhibitors may help treat liver fibrosis by targeting various pathways.
research Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development
The PP2A-B55α protein is essential for brain and skin development in embryos.
research Identification and expression of the target gene SLC24A2 of oar-miR-377 and its novel SNPs effects on wool traits in sheep
The TT genotype of a specific SNP in sheep is linked to better wool quality.
research Deep Insight of Design, Mechanism, and Cancer Theranostic Strategy of Nanozymes
Nanozymes show promise for effective and safe cancer treatment.
research Effects of Minoxidil on Cultured Human Skin Fibroblasts
Minoxidil slows down skin cell growth and may help treat scars and skin conditions.
research Genotoxicity of Rice Bran Oil Extracted by Supercritical CO2 Extraction
Rice bran oil extracted by supercritical CO2 is considered non-genotoxic.
research TLR3 signaling modulates immunomodulatory property of human periodontal ligament stem cells.
TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.
research Follikelhormone
Follicle Stimulating Hormone is important for fertility.
research Regulation of stem cell function by protein ubiquitylation
Protein ubiquitylation is crucial for controlling stem cell functions and could be targeted for cancer treatment.
research The Noggin null mouse phenotype is strain dependent and haploinsufficiency leads to skeletal defects
Noggin gene inactivation causes skeletal defects in mice, varying by genetic background.
research Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX 2 and SOX 9 in the human hair follicle
LHX2 and SOX9 identify unique hair follicle cell groups, crucial for hair maintenance.
research Impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis in noggin-overexpressing mice
Overexpressing noggin in mice causes severe osteoporosis.
research Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells
Researchers converted human embryonic stem cells into trophoblast stem cells using specific transcription factors.
research Finasteride Cream In Hirsutism
Finasteride cream reduces hair growth in women with hirsutism, but more research needed.
research Mesenchymal Stem Cells for Regenerative Medicine
Mesenchymal stem cells can help repair body tissues with low risk of rejection.
research Early lead exposure and pubertal development in a Mexico City population
Higher early lead exposure is linked to delayed puberty in girls.
research Progress in Relevant Growth Factors Promoting the Growth of Hair Follicle
Growth factors are crucial for hair follicle growth and development.
research Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
PP2Acα is essential for proper hair and skin development.
research Three-Dimensional Organoid System Transplantation Technologies in Future Treatment of Central Nervous System Diseases
Neural organoids show promise for future CNS disease treatments.
research miR-133a-3p and miR-145-5p co-promote goat hair follicle stem cell differentiation by regulating NANOG and SOX9 expression
miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.
research Case report on premature hair graying treated with Melitane 5% and oral hair supplements
Melitane 5% and hair supplements improved hair color in a 14-year-old with early graying.
research Mesenchymal cell replacement corrects thymic hypoplasia in murine models of 22q11.2 deletion syndrome
Replacing defective mesenchymal cells with normal ones fixes thymic growth issues in 22q11.2DS mouse models.
research Guidance for the management of hirsutism
Topical cream eflornithine 11.5% can slow hair growth and may help reduce hair removal frequency.
research Cooperation of TGF ‐β and FGF signalling pathways in skin development
TGF-β and FGF pathways are crucial for skin development and regeneration.
research Desmosomes in Developing Human Epidermis
Desmosomes are crucial for human skin development, increasing in density as the skin matures.
research Cases update: international roundup of recently filed cases and noteworthy rulings
Recent legal rulings favored Genentech, Teva, and upheld guidelines for patent term extensions.
research Single-Cell Proteomics Uncovers Dual Traits of Dermal Sheath Cells in Wound Repair
Dermal sheath cells help heal wounds by showing both skin and connective tissue traits.