176 citations
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September 2006 in “Stem Cells” BMP signaling prevents hair growth by stopping stem cell activation.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Astrotactin2 affects hair follicle orientation and skin cell polarity.
September 2025 in “Stem Cell Research & Therapy” TAZ boosts fat cell formation in goat stem cells by activating a specific signaling pathway.
10 citations
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May 2017 in “Wound Repair and Regeneration” Overexpression of ALK2 in hair follicles disrupts skin development and slows wound healing.
January 2024 in “Wiadomości Lekarskie” The ABI1 gene contributes to prostate cancer progression and treatment resistance.
266 citations
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January 2016 in “Development” YAP and TAZ are crucial for skin cell growth and repair.
82 citations
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January 2011 in “New Phytologist” VILLIN4 helps root hair growth by organizing actin with calcium.
22 citations
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March 2019 in “The Journal of Cell Biology” The Wave complex controls skin growth by suppressing certain signals.
130 citations
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March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
May 2025 in “Texas Digital Library (University of Texas)” Extracellular ATP promotes growth, while adenosine inhibits it in Arabidopsis plants.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Angiopoietin-1 helps hair follicle cells survive and grow, potentially treating hair loss.
20 citations
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December 2013 in “PLoS ONE” β1 integrin is essential for the survival, growth, and movement of human epithelial progenitor cells.
1 citations
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November 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Signals from skin cells controlled by Rac proteins help turn certain precursor cells into white fat cells.
2 citations
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Androgen signaling reduces Wnt activity, affecting prostate stem cell growth.
March 2026 in “Calcified Tissue International” The EDA pathway plays a key role in bone development by interacting with other signaling pathways.
140 citations
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November 2018 in “Pharmacology & Therapeutics” Using drugs to activate the Wnt/β-catenin pathway has potential for treating diseases but also presents challenges.
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October 2013 in “Journal of Investigative Dermatology” The OVOL1 gene, controlled by β-catenin, is crucial for creating hair follicles.
December 2011 in “University of Southern California Digital Library” High BMP signaling disrupts hair growth and balance in skin cells.
2 citations
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January 2025 in “动物学研究” YAP1 helps fat cell formation by influencing the Hippo pathway.
7 citations
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March 2020 in “PloS one” α-parvin is necessary for skin and hair growth and for the correct orientation of skin cells.
1 citations
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April 2024 in “Journal of Dermatological Science”
45 citations
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September 2012 in “Life Sciences” Aconiti Ciliare Tuber extract may help hair grow by activating a specific cell signaling pathway.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
1 citations
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June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
293 citations
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September 2004 in “Development” WNT signaling is crucial for starting mammary gland development.
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January 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Weak cell junctions disrupt hair follicle stem cell rest.
280 citations
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January 2004 in “The EMBO Journal” AGC2-1 protein is essential for root hair growth in Arabidopsis.
5 citations
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December 2020 in “Gene” ANXA1 influences hair growth in mice through the EGF signaling pathway.
1 citations
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October 2020 in “Research Square (Research Square)” Abnormal Wnt signaling in hair follicle stem cells can lead to acne-like cysts.
14 citations
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November 2024 in “International Journal of Molecular Sciences” YAP and TAZ proteins control skin cell growth and repair.