Pvalb8 is essential for zebrafish hearing and hair cell development, and its mutation causes hearing loss.
5 citations
,
January 2024 in “Reproductive Medicine and Biology” Androgen and Wnt signals are crucial for developing and functioning male genitalia and erectile tissues.
67 citations
,
December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
19 citations
,
January 2013 in “International journal of medical sciences” Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
1 citations
,
February 2021 in “Farmacja Polska” Janus kinase inhibitors show promise in treating autoimmune skin diseases.
11 citations
,
June 2019 in “Tissue & Cell” Hair stem cells produce a protein called COL17A1 that plays a key role in their development and is linked to hair thinning and baldness.
76 citations
,
June 2018 in “EMBO Reports” YAP and TAZ proteins are necessary for the development of two types of skin cancer.
35 citations
,
February 2019 in “Cell Communication and Signaling” BMP6 and Wnt10b control whether hair follicles are resting or growing.
5 citations
,
January 1993 in “PubMed” Retinoic acid can change skin structures in vertebrates, like turning scales into feathers or hair buds into glands.
4 citations
,
February 2023 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The study found that certain mutations in the vitamin D receptor can cause rickets and potentially affect hair growth.
January 2007 in “Queen Mary Research Online (Queen Mary University of London)” GLI and EGF signalling affect Basal Cell Carcinoma development and could be therapeutic targets.
4 citations
,
March 2014 in “The FASEB Journal” The HIF-2α/ARNT complex is important for hair follicle development by controlling cell growth.
January 2004 in “Kölner Universitäts PublikationsServer (Universität zu Köln)” Collagen XVII and CD151 affect cell movement, with CD151 inhibiting migration when bound to integrins.
26 citations
,
December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
56 citations
,
September 2014 in “Molecular Endocrinology” Vitamin D receptor is essential for hair growth signaling.
January 2006 in “Chieh P'ou Hsueh Pao” Beta-catenin boosts hair follicle cell growth by increasing c-myc expression.
April 2019 in “Journal of Investigative Dermatology” Calcium signals and SHH guide the direction of feather growth in chicken skin.
65 citations
,
February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Anti-acne medications may work by reducing the activity of a protein involved in acne development.
13 citations
,
February 2018 in “Plastic and Reconstructive Surgery” The study found that a specific signaling pathway helps skin wounds heal faster but may lead to larger scars.
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
30 citations
,
April 2020 in “Stem Cell Research & Therapy” PI3K/Akt pathway is crucial for hair growth and regeneration.
July 2023 in “Current Issues in Molecular Biology” Escin may help treat hair loss by boosting a specific cell growth pathway.
44 citations
,
January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.
4 citations
,
April 2024 in “The Journal of Cell Biology” Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.
207 citations
,
March 2012 in “Development” Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.
July 2024 in “Journal of Investigative Dermatology” Wnt and SHH signals together influence hair follicle cell development, offering insights for hair loss treatment.
47 citations
,
September 2012 in “Human molecular genetics online/Human molecular genetics” Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.
475 citations
,
October 2006 in “Proceedings of the National Academy of Sciences” Folliculin helps regulate energy and nutrient sensing, impacting Birt–Hogg–Dubé syndrome.
April 2008 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The vitamin D receptor helps control hair growth and may protect against certain skin tumors.