22 citations
,
June 2002 in “Journal of Medicinal Chemistry” Compounds 15, 20, and 25 are strong inhibitors of human steroid 5α-reductase type 2.
73 citations
,
July 1977 in “Archives of Dermatology” Applying safflower oil to the skin reversed fatty acid deficiency symptoms in 21 days.
6 citations
,
October 2014 in “Experimental Dermatology” Prostaglandins and the enzyme AKR1C3 could play a role in skin cancer and hair loss, and further research is needed to understand these mechanisms.
August 2018 in “Journal of Investigative Dermatology” Polyunsaturated fatty acids, like arachidonic acid and eicosapentaenoic acid, can promote hair growth and may help treat hair loss.
June 2006 in “Annales de Dermatologie et de Vénéréologie” Tranexamic acid effectively reduced swelling episodes in a girl with a rare form of hereditary angioneurotic edema.
August 2025 in “The Nishinihon Journal of Dermatology” Prednisolone treatment improved symptoms and hair regrowth in a patient with Cronkhite-Canada Syndrome.
May 2026 in “BMC Medicine” ACOD1 deficiency worsens hair loss by causing cell aging and mitochondrial problems, but 4-OI may help.
2 citations
,
April 2024 in “Medical Journal Armed Forces India” 4 citations
,
February 2025 in “Molecular Medicine” 5-aminolevulinic acid therapy reduces acne by decreasing fat production in skin cells.
25 citations
,
November 1994 in “The Journal of Dermatologic Surgery and Oncology” Acetone is not more effective than other degreasers and is more flammable.
September 1988 in “Inpharma (Balgowlah)” Retinoids are effective for acne but can cause serious side effects.
21 citations
,
August 2002 in “British Journal of Ophthalmology” Intralesional cidofovir may be a viable alternative treatment for SCC.
47 citations
,
September 2013 in “Aaps Pharmscitech” Improved hair loss treatment using special particles and surfactants.
2 citations
,
May 2020 in “Journal of the American Academy of Dermatology” Hair shaft changes may be linked to CCCA, but their role is unclear.
3 citations
,
April 2025 in “International Journal of Pharmaceutics” Nanocrystals improve alopecia areata treatment by better targeting hair follicles.
7 citations
,
May 2016 in “European Polymer Journal” The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
7 citations
,
June 2020 in “Experimental dermatology” Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.
April 2026 in “Clinical Case Reports” A strict gluten-free diet can improve liver issues in celiac disease.
1 citations
,
June 2014 in “Vìsnik farmacìï” A medicinal cosmetic product for treating Androgenetic Alopecia was developed using plant-based substances, Saw palmetto and Japanese Sophora, with pumpkin seed oil and stabilizers like Carbopol, sodium alginate, xanthan gum, Tween-20 and cetyl alcohol.
22 citations
,
September 2022 in “International Journal of Nanomedicine” CUR-loaded micelles improve skin delivery and effects of curcumin for pain and infections.
1 citations
,
January 2012 in “Human health handbooks” Linoleic acid is important for healthy skin, and while most people get enough from their diet, not having enough can cause skin and hair problems.
2 citations
,
September 2023 in “Foods” Microcapsules and effervescent tablets make insect lipids easier to consume.
20 citations
,
December 2012 in “Journal of molecular structure” The study found that thioglycolic acid breaks down hair bonds more consistently than l-cysteine, which is less damaging to hair.
88 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” 41 citations
,
January 2000 in “Hormone Research in Paediatrics” Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.
5 citations
,
September 2013 6 citations
,
July 2005 in “Acta Ophthalmologica Scandinavica” Mitochondriopathy may cause eyelash loss.
1 citations
,
February 2009 in “Journal of Investigative Dermatology” Lipase H is important for hair follicle function and shaping hair fibers.
18 citations
,
January 1987 in “PubMed” Zinc deficiency in alcoholic cirrhosis patients causes skin issues and other symptoms, which improve with zinc treatment.
30 citations
,
May 2008 in “International Journal of Dermatology” Lipedematous alopecia causes permanent hair loss due to increased scalp fat.