February 2026 in “Journal of Cosmetic Dermatology” Polynucleotide injections improved eye wrinkles with few side effects.
September 2025 in “Journal of Zhejiang University (Medical Sciences)” Peripheral nerves are essential for skin wound healing and future treatments could improve by focusing on nerve and blood vessel regeneration.
19 citations
,
September 2006 in “Journal of Neurophysiology” Neurosteroids help balance brain signals when certain inhibitions are reduced.
5 citations
,
January 2020 in “Journal of Dermatology and Dermatologic Surgery” Caffeine may benefit skin and hair health but more research is needed to confirm its effectiveness in dermatology.
3 citations
,
April 2023 in “Frontiers in Pharmacology” ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.
1 citations
,
October 2022 in “Springer eBooks” Testosterone is key for male sexual function, and treating hormone imbalances can improve sexual issues.
November 2025 in “Journal of Pharmacy and Pharmacology” PEDF reduces oxidative damage and supports stem cells.
August 2023 in “Journal of Cosmetic Dermatology” Some plants like spinach, broccoli, and matcha may boost the effectiveness of the hair growth drug minoxidil.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
277 citations
,
December 2019 in “Frontiers in Immunology” JAK inhibitors show promise for treating skin disorders like alopecia, eczema, and psoriasis.
90 citations
,
February 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Interleukin-1 increases keratin K6 production in skin cells.
18 citations
,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
6 citations
,
August 2022 in “International journal of molecular sciences” α-Phellandrene may help prevent hair loss by increasing growth factors and cell growth in hair cells through a specific signaling pathway.
2 citations
,
May 2023 in “Photobiomodulation, photomedicine, and laser surgery” Light therapy is effective and safe for treating skin color disorders like vitiligo and dark spots.
Metformin shows promise for treating skin conditions, but more research is needed.
November 2025 in “ACS Omega” Teak leaf extract may help hair growth and reduce inflammation safely.
August 2024 in “Journal of Controlled Release” A new treatment using hybrid vesicles with gold nanoparticles and finasteride significantly improves hair regrowth for androgenetic alopecia.
April 2024 in “Frontiers in endocrinology (Lausanne)” Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.
August 2023 in “MOJ women's health” Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
July 2023 in “Journal of Cutaneous and Aesthetic Surgery” Combining platelet-rich plasma with other treatments may improve hair growth in people with hair loss, but more research is needed.
The combination therapy improved hair growth and thickness in people with androgenetic alopecia.
August 2023 in “Journal of Cosmetic Dermatology” Using a laser with minoxidil was more effective for hair loss than minoxidil alone.
505 citations
,
October 2011 in “Journal of clinical oncology” MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.
95 citations
,
August 2013 in “Journal of Investigative Dermatology” HPT axis hormones boost mitochondrial function and growth in hair follicles, potentially aiding hair health.
43 citations
,
July 2023 in “Pharmaceuticals” Caffeine can boost health, prevent diseases, and improve performance, with new methods enhancing its benefits.
34 citations
,
June 2015 in “Journal of cardiovascular pharmacology and therapeutics” Direct vasodilators and sympatholytic agents are still useful for certain conditions despite being less common due to side effects and newer drugs.
23 citations
,
June 2015 in “Experimental Dermatology” Pericytes can both help and hinder wound healing, needing more research for effective use in treatments.
18 citations
,
May 2023 in “Preprints.org” Caffeine can boost health but may cause side effects like high blood pressure and migraines.
18 citations
,
May 2022 in “Stem Cell Research & Therapy” Green OLED light improves stem cell effectiveness for better wound healing.
18 citations
,
June 2017 in “Oncotarget” Digoxin is linked to a higher risk of anemia in patients with atrial fibrillation and heart failure.