TLDR Azelaic acid is effective for treating rosacea, acne, and melasma.
Azelaic acid (AZA) is a naturally occurring dicarboxylic acid with various physiological activities, such as antibacterial, anti-keratinizing, antimelanogenic, antioxidant, and anti-inflammatory effects. It is commonly used in dermatology and is FDA-approved for treating papulopustular rosacea. Additionally, AZA is effective in managing acne vulgaris and melasma. This review highlights the mechanisms of action and clinical applications of AZA, providing theoretical support for its use in clinical and cosmetic settings and encouraging further research.
June 2024 in “International journal of nanomedicine” Azelaic acid micro/nanocrystals, especially with ultrasound and salicylic acid, greatly improve acne treatment.
December 2023 in “Siriraj Medical Journal” 5% Azelaic acid is as effective as 2% Minoxidil for female pattern hair loss and could be an alternative for those allergic to Minoxidil or pregnant.
January 2023 in “Postępy Dermatologii i Alergologii” Azelaic acid treats acne, rosacea, and hyperpigmentation with minimal side effects.
56 citations
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July 2020 in “Journal of Dermatological Treatment” Azelaic acid is safe and effective for treating rosacea and other skin issues.
164 citations
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February 2019 in “Anais Brasileiros de Dermatologia” Adult female acne requires personalized treatment and maintenance to prevent relapse.
27 citations
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January 2005 in “American Journal of Clinical Dermatology” Azelaic acid and anthralin are similarly effective for treating patchy hair loss.
