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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

HPV does not cause aggressive cancer in RDEB patients.

Mutations at Val-889 and Arg-752 disrupt key interactions in the androgen receptor, affecting its function.

CDK inhibitors may help treat ARDS and psoriasis but need more testing for safety and effectiveness.

A gene-based model predicts lung adenocarcinoma outcomes and helps guide treatment decisions.

Enfortumab vedotin can cause skin issues, especially in older males, needing early monitoring.

Male hormones control a specific gene in hamster skin, with different hormones having varying effects.

DHT enhances androgen receptor activity more than testosterone, and MAGE-11 influences this activity through specific interactions.

Raltitrexed conjugates are less potent than the free drug but more effective at high concentrations.

A person with a new mutation in the SCN1A gene developed brain inflammation after COVID-19.

Introducing the rat OTC gene normalized hair growth in SPF-ASH mice.

COVID-19 may cause hair loss by affecting hair follicles.

CD8+ T cells expand significantly in alopecia areata, suggesting new treatment targets.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Suppressing the HGPS mutation may improve symptoms and suggest reversibility.

Intralesional cidofovir might be a viable alternative treatment for certain conditions.

MSC-derived EVs show promise for therapy, but production and understanding need improvement.

The over-the-counter supplement DHEA could make COVID-19 worse, especially in diabetics and people with G6PD deficiency.

Increased TEMRA cells can predict treatment outcomes in rapidly progressive alopecia areata.

A specific type II hair keratin was identified and found in hair cortex and tongue cells.

Men may be more vulnerable to severe COVID-19 due to genetic and hormonal factors, but more research is needed.

Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.

A mouse model for studying scleroderma in chronic graft-versus-host disease was successfully created.

Thyroid-related genes are active in skin cells and may affect autoimmune conditions.

BCG site reactions after COVID-19 mRNA vaccination are mild, temporary, and likely under-reported.

Viruses continue to challenge human health despite medical advances.

Certain interactions help prepare the androgen receptor for pairing and activation, which is important for its role in development and disease.

ATR12-351 ointment safely delivers LEKTI protein to the skin, reducing enzyme activity in Netherton syndrome.

HA-stimulated stem cell vesicles improved hair growth in male mice with androgenetic alopecia.