research Prepregnancy Phenotype and Physiological Characteristics in PCOS
Women with PCOS have different body composition and some metabolic differences compared to healthy women.
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870-900 / 1000+ resultsresearch Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster.
TCDD reduces EGF receptor activity and causes various developmental changes in animals.
research Hormonal Profile and Anthropometric Indices As Determinants of Metabolic Risk in Polycystic Ovary Syndrome: A Prospective Observational Study
Women with PCOS have hormonal imbalances and increased central obesity, highlighting the need for early detection and management.
research Association of biochemical hyperandrogenism with type 2 diabetes and obesity in Chinese women with polycystic ovary syndrome
High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.
research Metabolic risk in PCOS: phenotype and adiposity impact
Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
research Autotaxin–lysophosphatidic acid– LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.
research Advances in mitochondria-centered mechanism behind the roles of androgens and androgen receptor in the regulation of glucose and lipid metabolism
Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.
research 502 The stress-responsive secretory protein adrenomedullin 2 potently induces cell cycle arrest and apoptosis in human hair follicles
Adrenomedullin 2 stops cell growth and causes cell death in human hair follicles.
research Nonclassic adrenal hyperplasia
Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.
research Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis
High-concentration cell-free adipose extract reduces scar formation and improves scar appearance.
research Investigation Bisphenol A and Phthalate Levels in Idiopathic Hyperandrogenemia
Higher BPA levels may be linked to idiopathic hyperandrogenemia in women.
research ADRENOCORTICAL FUNCTION IN PUBERTY Serum ACTH, Cortisol and Dehydroepiandrosterone in Girls and Boys
Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.
research An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess
Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.
research Changes in expression of the neuropeptide Y Y1 receptor gene in the medial amygdala of transgenic mice during pregnancy and after delivery
Pregnancy-related hormone changes affect Y1 receptor gene expression in mice.
research A case of severe hyperandrogenism, acanthosis nigricans and overt diabetes: the use of non-invasive methods for diagnosis, pathogenesis and management
Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
research The Force Is Strong with This One: Metabolism (Over)powers Stem Cell Fate
Metabolism plays a key role in determining stem cell fate.
research Environment of the Anagen Follicle
The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.
research Dehydroepiandrosterone- and glucose-6-phosphate-dehydrogenases in the hair cycle of the rat
research Therapeutic Potential of Adipose-Derived Stem Cells and Their Secretome in Reversible Alopecias: A Systematic Review
Adipose-derived stem cells may help with hair loss, but more research is needed.
research Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte‐mediated growth inhibition of anagen‐phase vibrissa hair
Leptin from skin fat can slow hair growth during certain phases.
research The Agouti Gene in Obesity: Central and Peripheral Mechanisms, and Therapeutic Implications
The agouti gene may help understand and treat obesity.
research Role of Stearoyl-CoA Desaturase-1 in Skin Integrity and Whole Body Energy Balance
SCD1 is crucial for skin health and overall energy balance.
research Neuroimmunoregulation of Androgens in the Adrenal Gland and the Skin
Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
research Age‐dependent regulation by androgens of gene expression in the anterior hypothalamus and stress‐induced release of adrenal hormones in adolescent and adult male rats
Testosterone affects stress hormone levels differently in adolescent and adult male rats.
research 498 Innate immunity activation of sebocyte cells by living bacteria. Evidence of a potential immunosuppressive effect of DHT
DHT may reduce inflammation caused by certain bacteria in skin cells.
research Visual Vignette
A 13-year-old boy with Cushing syndrome has high cortisol levels from a pituitary gland issue and underdeveloped sexual characteristics.
research Serum Adiponectin and Leptin in Patients with Alopecia Areata
Lower adiponectin and higher leptin levels may predict hair loss in alopecia areata.
research Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome
Genetic risk for PCOS can affect children's growth, metabolism, and development from early life into adulthood.
research Aging in the sebaceous gland
Sebaceous glands age due to genetic and environmental factors, affecting sebum production and composition.
research Phenotypic modulation of human hair matrix cells (trichocytes) by environmental influence in vitro and in vivo.
Human hair cells can change based on their environment, especially interactions with certain skin cells.