April 2018 in “Journal of Investigative Dermatology” Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.
March 2024 in “Middle East Fertility Society Journal/Middle East Fertility Society Journal ” PCOS patients have more central body fat, which can be effectively measured using DEXA.
16 citations
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April 2007 in “Journal of Obstetrics and Gynaecology Research” Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.
1 citations
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October 2014 in “Skin Pharmacology and Physiology” People with alopecia areata have higher levels of osteopontin, which might be important in the disease's development, but this doesn't relate to how severe the disease is.
MFN2 mutations cause mitochondrial problems, leading to more upper body fat and lower leptin levels.
September 2024 in “PubMed” Certain RNAs may help diagnose alopecia areata by affecting keratin genes.
5 citations
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October 2024 in “Reumatismo” Upadacitinib significantly improved alopecia universalis and psoriatic arthritis in a patient.
238 citations
,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
High insulin levels are more common and a better predictor of carbohydrate issues in women with PCOS than glucose tolerance tests.
7 citations
,
January 1986 in “Prenatal Diagnosis” Fetal skin biopsy can help diagnose protein-related disorders before birth.
April 2018 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
May 2025 in “Frontiers in Pharmacology” Targeting gut microbiome and metabolome may help treat autoimmune skin diseases like alopecia areata.
November 2019 in “Клітинна та органна трансплантологія” Adipose-derived stem cells are useful in aesthetic medicine and dermatology for improving skin and tissue appearance.
42 citations
,
September 2007 in “The Journal of Clinical Endocrinology and Metabolism” The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Adipose stem cell exosomes can effectively reduce facial redness and improve skin health in atopic dermatitis patients.
February 2021 in “International journal of regenerative medicine” A new method using fat tissue cells may help treat hair loss.
April 2025 in “Egyptian journal of Immunology” Calprotectin levels are higher in alopecia areata patients, indicating systemic inflammation.
47 citations
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July 2023 in “Nature Genetics”
7 citations
,
September 2020 in “Journal of Cosmetic Dermatology” Serum biomarkers like insulin-like growth factor-1 and vitamin D may help diagnose androgenetic alopecia.
34 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
2 citations
,
April 2024 in “Medical Journal Armed Forces India”
2 citations
,
September 2008 in “Fertility and Sterility” Clinical signs of excess male hormones and actual hormone levels in the blood do not always match in women with polycystic ovary syndrome.
89 citations
,
April 2023 in “Forensic Science International Genetics” Forensic DNA Phenotyping can now better predict appearance, ancestry, and age from DNA, but more research is needed for precise police use.
77 citations
,
September 1983 in “Acta Paediatrica” Dexamethasone effectively normalizes elevated steroid levels in girls with premature adrenarche.
118 citations
,
April 2020 in “Stem Cell Research & Therapy” IFNγ-primed MSC secretomes can improve joint health by reducing inflammation and supporting tissue repair.
2 citations
,
April 2023 in “BMC endocrine disorders” The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
April 2019 in “Journal of Investigative Dermatology” Removing REDD1 in mice increases skin fat by making fat cells larger and more numerous.
April 2025 in “Dermatology Practical & Conceptual” Alopecia areata patients have higher systemic inflammation, even in mild cases.
8 citations
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October 2023 in “Frontiers in Immunology” Certain cytokines may cause or be affected by immune skin diseases, suggesting possible new treatments.