August 2015 in “Free Radical Biology and Medicine” The study suggests that higher levels of SIRT1 and SIRT2 may improve overall cell health and aging processes.
437 citations
,
August 2014 in “Cell metabolism” Turning white fat into brown-like fat could help fight obesity and type 2 diabetes.
39 citations
,
July 2021 in “Stem Cell Research & Therapy” Using fat stem cells and blood cell-rich plasma together improves healing in diabetic wounds by affecting cell signaling.
10 citations
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January 2023 in “SAGE Open Medical Case Reports” Upadacitinib may effectively treat both alopecia universalis and Crohn's disease.
October 2024 in “Journal of Medical and Scientific Research” Higher prolactin levels are linked to psoriasis, alopecia areata, and vitiligo severity.
7 citations
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October 2024 in “Acta Dermato Venereologica” Higher inflammation markers are linked to more severe alopecia areata.
4 citations
,
February 2024 in “Anais Brasileiros de Dermatologia”
October 2010 in “Reproductive Biomedicine Online” A new method can almost perfectly distinguish adenomyosis from similar conditions using blood tests.
May 2023 in “Journal of Pakistan Medical Association” People with polycystic ovary syndrome have higher levels of Gremlin-1.
October 2010 in “Reproductive Biomedicine Online” Women with PCOS and androgenic alopecia have different triglyceride metabolism compared to those without hair loss.
January 2024 in “International Journal of Dermatology Research” Acne in teens is linked to insulin resistance, especially in older males.
3 citations
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July 2019 in “Experimental Dermatology” Hair loss patients may have different polyamine levels in various scalp areas.
May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Linoleic acid and magnesium are key in alopecia areata progression, and tofacitinib can help by affecting their pathway.
135 citations
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March 1984 in “Fertility and sterility” Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.
January 2026 in “Biomedicines” Dysregulated lipid metabolism may play a role in male pattern baldness.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin-511 is involved in psoriasis development and can be regulated by cannabinoid receptor type 1.
September 2020 in “Research Square (Research Square)” Enhanced stem cells from the placenta can reduce fat buildup in eye tissue for Graves' disease.
46 citations
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November 2014 in “The Journal of Clinical Endocrinology & Metabolism” Men with isolated hypogonadotropic hypogonadism have partial steroid deficiencies, while those with panhypopituitarism have severe deficiencies.
35 citations
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November 1989 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Epitestosterone may act as a weak antiandrogen and can inhibit an enzyme involved in testosterone metabolism.
5 citations
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June 2024 in “Pharmacological Research” FOL-026 peptide may help hair growth and cardiovascular health by improving blood flow and cell functions.
July 2025 in “Arab Board Medical Journal” NF-κB levels can help diagnose and assess the severity of androgenetic alopecia.
22 citations
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January 2019 in “Hormone and Metabolic Research” Measuring certain hormones can help predict metabolic risk in women with PCOS.
July 2022 in “World Journal of Advanced Research and Reviews” Piptadeniastrum africanum and Cordia plathytyrsa can increase testosterone without major metabolic changes, but may affect triglycerides and creatinine.
April 2019 in “Journal of Investigative Dermatology” Dihydrotestosterone (DHT) increases oil production in skin cells by activating mTOR, and mTOR inhibitors can reduce this effect.
June 2024 in “International Journal of Dermatology” Upadacitinib may effectively treat resistant lichen planopilaris.
February 2026 in “South Asian Research Journal of Biology and Applied Biosciences” Alopecia areata patients have higher hormone levels, suggesting hormonal screening could help in treatment.
March 2020 in “Research Square (Research Square)” Type 2 diabetic stem cells can still help heal wounds effectively.
July 2024 in “Journal of Investigative Dermatology” Inhibiting PDE8A may help treat hair loss by boosting fat cell growth and hair regeneration.
April 2019 in “Journal of the Endocrine Society” Androgens and estrogens are crucial for insulin secretion in males.
June 2025 in “Research Square (Research Square)” HAIR-AN syndrome mainly affects obese women and can be improved with early diagnosis and treatment using insulin-sensitizing agents.