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Efficacy, Safety, and Tolerability of Upadacitinib in Adults and Adolescents With Severe Alopecia Areata: Results From the Randomized, Placebo-Controlled, Double-Blind Phase 3 Program (UP-AA)

research Efficacy, Safety, and Tolerability of Upadacitinib in Adults and Adolescents With Severe Alopecia Areata: Results From the Randomized, Placebo-Controlled, Double-Blind Phase 3 Program (UP-AA)

November 2025 in “SKIN The Journal of Cutaneous Medicine”

Upadacitinib effectively treats severe alopecia areata and is safe.

Application of Design of Experiments (DoE) for Optimization of Analytical Method for Quantification of Minoxidil by HPLC

research APLICAÇÃO DE PLANEJAMENTO DE EXPERIMENTOS (DoE) PARA OTIMIZAÇÃO DE MÉTODO ANALÍTICO PARA QUANTIFICAÇÃO DE MINOXIDIL POR CLAE

January 2023 in “Anais do Congresso Brasileiro Interdisciplinar em Ciência e Tecnologia.”

Optimizing the method improved minoxidil measurement accuracy and efficiency.

Penetration and Distribution of Three Lipophilic Probes in Human Skin Focusing on the Hair Follicle

research Penetration and distribution of three lipophilic probes in vitro in human skin focusing on the hair follicle

54 citations , October 2002 in “Journal of controlled release”

Medium lipophilic substances penetrate skin best, and adding ethanol can increase delivery to hair follicles.

research Synergistic effect of carbodiimide and dehydrothermal crosslinking on acellular dermal matrix

61 citations , January 2013 in “International Journal of Biological Macromolecules”

Combining DHT and EDC improves the strength and stability of PADM scaffolds for tissue engineering.

research Differential expression and functionality of ATP-binding cassette transporters in the human hair follicle

25 citations , November 2014 in “British Journal of Dermatology”

Certain transporters are found in human hair follicles and may affect hair growth and loss.

research Relative binding affinity of novel steroids to androgen receptors in hamster prostate

5 citations , January 2005 in “Journal of Enzyme Inhibition and Medicinal Chemistry”

New steroids were effective in blocking male hormone receptors in hamster prostates.

Enhanced Ectodysplasin-A Receptor Signaling Alters Multiple Fiber Characteristics to Produce the East Asian Hair Form

research Enhanced ectodysplasin-A receptor (EDAR) signaling alters multiple fiber characteristics to produce the East Asian hair form

98 citations , June 2008 in “Human mutation”

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

research Enhancement of In Vitro Hair Shaft Elongation in Follicles Stored in Buffers That Prevent Follicle Cell Apoptosis

January 2004 in “Dermatologic Surgery”

Storing hair follicles in a special buffer with certain inhibitors can increase hair growth and improve transplant results.

research Finasteride nano-transferosomal gel formula for management of androgenetic alopecia: ex vivo investigational approach

24 citations , July 2018 in “Drug Design Development and Therapy”

NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.

research Lung-Targeted Delivery of Cepharanthine by an Erythrocyte-Anchoring Strategy for the Treatment of Acute Lung Injury

8 citations , August 2022 in “Pharmaceutics”

Erythrocyte-anchored nanoparticles improved Cepharanthine delivery and effectiveness for treating acute lung injury.

Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation

research Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation

18 citations , October 2018 in “Nutrients”

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

research Formulation and evaluation of repurposed ketoconazole‐loaded transferosomal gel for enhanced trichogenic effects

April 2025 in “Clinical and Translational Discovery”

The ketoconazole gel improved hair growth and is a promising treatment for hair loss.

research 5PSQ-117 Effectiveness of baricitinib in alopecia areata

March 2025

Baricitinib effectively treats alopecia areata, with over half of patients improving after 52 weeks.

research Microencapsulated human hair dermal papilla cells: a substitute for dermal papilla?

25 citations , April 2008 in “Archives of Dermatological Research”

Encapsulated human hair cells can substitute for natural hair cells to grow hair.

research Treatment of Steroid-Resistant Beard-Restricted Alopecia Areata with Baricitinib

March 2024 in “Skin”

Baricitinib helped treat a man's beard hair loss when steroids didn't work.

research Innovating alopecia treatment: nanostructured lipid carriers as advanced delivery platforms

2 citations , January 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology”

Nanostructured lipid carriers can improve alopecia treatment by enhancing drug delivery and promoting hair growth.

research Editorial: Software survey section

January 1995 in “Expert Systems with Applications”

research Preparation, Optimization, In vitro Evaluation and Ex vivo Permeation Studies of Finasteride loaded gel Formulations Prepared by using Response SurfaceMethodology

3 citations , September 2018 in “Current Drug Delivery”

The combination of propylene glycol and Tween® 80 improves finasteride gel effectiveness.

research A Concept on The Development of The DRDE Series of Compounds for Skin Diseases Using In-Silico ADME And Drug-Likeness Analysis

March 2026 in “Preprints.org”

DRDE-07 shows promise for treating skin diseases due to its favorable properties.

research Follicular Targeting–A Promising Tool in Selective Dermatotherapy

109 citations , November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Targeting hair follicles can improve skin treatments and reduce side effects.

Effects of Skin Environmental Changes by Steam Towel, Ethanol, L-Menthol and Carpronium on the Drug Behavior in Minoxidil Nanoparticles-Applied Mice

research Effects of Skin Environmental Changes by Steam Towel, Ethanol, l-Menthol and Carpronium on the Drug Behavior in the Minoxidil Nanoparticles-applied Mice

August 2022 in “Yakugaku zasshi”

Using a steam towel, l-menthol, and carpronium before applying minoxidil nanoparticles can increase its absorption and potentially improve hair growth.

research Exploiting Recent Trends in the Treatment of Androgenic Alopecia through Topical Nanocarriers of Minoxidil

1 citations , November 2022 in “Aaps Pharmscitech”

research The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches

6 citations , November 2023 in “JCI Insight”

Exogenous stem cells can effectively integrate into hair follicles, promoting hair growth.

research Hyaluronic Acid Microneedles Loaded with ChineseHerbalExtracts as an Intradermal Delivery System for Hair Regeneration

April 2025 in “OPAL (Open@LaTrobe) (La Trobe University)”

Hyaluronic acid microneedles with herbal extracts may effectively promote hair growth for treating hair loss.

Hair Growth Stimulatory Effect by a Combination of 5-Aminolevulinic Acid and Iron Ion

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