research Alopecia: unapproved treatments or indications
Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
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research The effect of finasteride and dutasteride on the synthesis of neurosteroids by glioblastoma cells
Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.
research Complex Changes in the Apoptotic and Cell Differentiation Programs during Initiation of the Hair Follicle Response to Chemotherapy
Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.
research Suety and Spreading-Stromal Hyperplasia and Hyperthecosis Ovary
These ovarian conditions cause high testosterone levels.
research General Dermatology
The document explains various skin conditions and their treatments.
research The pathophysiology of polycystic ovary syndrome
Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.
research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth
Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.
research Indications for a brain‐hair follicle axis: inhibition of keratinocyte proliferation and up‐regulation of keratinocyte apoptosis in telogen hair follicles by stress and substance P
Stress can cause hair loss by negatively affecting hair follicles and this effect might be reversed with specific treatments.
research Androgen receptor–mediated inhibition of cutaneous wound healing
Lowering testosterone speeds up wound healing in male mice.
research Dermatological Manifestations of Stress in Normal and Psychiatric Populations
Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.
research 5α-Reductase inhibitors alter steroid metabolism and may contribute to insulin resistance, diabetes, metabolic syndrome and vascular disease: a medical hypothesis
Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.
research Endocrine systems of the skin
The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
research The laboratory in the multidisciplinary diagnosis of differences or disorders of sex development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering
Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.
research COVID-19 and endocrine and metabolic diseases. An updated statement from the European Society of Endocrinology
People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.
research Harnessing neuroendocrine controls of keratin expression: A new therapeutic strategy for skin diseases?
Using neurohormones to control keratin can lead to new skin disease treatments.
research Diseases on Hair Follicles Leading to Hair Loss Part I: Nonscarring Alopecias
Common types of non-scarring hair loss have various causes and treatments, but more effective solutions are needed.
research Topical Antiandrogen Therapies for Androgenetic Alopecia and Acne Vulgaris
Topical therapies show promise for hair loss and acne treatment with minimal side effects.
research Retinol-binding protein 4, leptin, and insulin resistance in idiopathic hirsutism and hirsute women with polycystic ovary syndrome
Women with idiopathic hirsutism and PCOS have higher RBP4 levels, and PCOS is linked to greater insulin resistance; weight management may help both conditions.
research The Medicolegal Examination of Hairs
Hair analysis can offer clues about a person, but individual differences limit making precise identifications.
research Macrophages as central mediators of sympathetic neuro-immune interplay in autoimmunity
Restoring nerve-macrophage communication may help treat autoimmune diseases.
research Neuroendocrine Controls of Keratin Expression in Human Skin
Neurohormones help control skin health and could treat skin disorders.
research Hormonal Therapy for Acne
Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
research PCOS: update and diagnostic approach
The document concludes that more research is needed to fully understand the causes of PCOS.
research Management OF Patients with Polycystic Ovary Syndrom
PCOS management involves medication, lifestyle changes, and personalized treatment to address symptoms and improve health.
research Melatonin membrane receptors in peripheral tissues: Distribution and functions
Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
research A Review of Coumarin Derivatives in Pharmacotherapy of Breast Cancer
Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
research The cutaneous serotoninergic/melatoninergic system: securing a place under the sun
Human skin can make serotonin and melatonin, which help protect and maintain it.