183 citations
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March 1982 in “JAMA” Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.
147 citations
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October 2004 in “Experimental dermatology” Hormones like testosterone affect skin functions and can cause skin issues when in excess; treatments to manage these effects are only somewhat effective.
118 citations
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September 2004 in “Clinics in Dermatology” Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.
116 citations
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April 2002 in “American journal of veterinary research” Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.
97 citations
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November 1986 in “Journal of Steroid Biochemistry” Antiandrogens affect androgen-dependent body functions and are used for various medical conditions, with some risks like fetus feminization, but new forms like 17α-propylmesterolone show promise for acne without systemic effects.
96 citations
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October 1987 in “The Journal of Clinical Endocrinology & Metabolism” Chronic GnRHa treatment can help manage endometrial hyperplasia and reduce ovarian androgen excess in PCO patients.
95 citations
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September 1979 in “Acta Paediatrica” Girls have higher DHEA levels earlier in puberty than boys, indicating earlier development.
90 citations
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May 2019 in “Drugs” Long-term use of azole antifungals can cause hair loss, hormonal imbalances, and severe skin reactions.
84 citations
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September 2014 in “European journal of endocrinology” Doctors should check for serious tumor causes of high androgen levels in postmenopausal women and more research is needed on this condition.
77 citations
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June 2006 in “Best Practice & Research Clinical Endocrinology & Metabolism” The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
67 citations
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September 2008 in “Dermatologic therapy” Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.
62 citations
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January 2010 in “Hormone research in paediatrics” Genetic screening is crucial for accurately diagnosing APS-1 due to its varied symptoms.
57 citations
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April 2009 in “The Journal of Steroid Biochemistry and Molecular Biology” Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.
57 citations
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January 1995 in “The American journal of medicine” Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.
55 citations
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August 2009 in “Journal of Feline Medicine and Surgery” Cats with adrenal tumors may have both hyperaldosteronism and hyperprogesteronism.
52 citations
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March 1987 in “Journal of the American Academy of Dermatology” High DHEA-S levels may cause hair loss in young men.
44 citations
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February 2016 in “Zoology” Hair cortisol levels in primates are useful for stress assessment but vary by age, sex, species, and hair collection methods.
42 citations
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November 2019 in “Frontiers in Endocrinology” The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.
42 citations
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October 2004 in “Experimental and Clinical Endocrinology & Diabetes” The main cause of excessive hair growth in Turkish women is Polycystic ovary syndrome, but in about one fifth of cases, the reason for high male hormone levels is unknown.
41 citations
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January 2000 in “Hormone Research in Paediatrics” Cortisone reductase deficiency can cause high androgen and cortisol levels and may be missed in women with similar symptoms.
40 citations
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October 2004 in “Veterinary Dermatology” Trilostane treatment led to full hair regrowth in most Pomeranians and all miniature poodles with alopecia X.
40 citations
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March 1982 in “British Journal of Dermatology” Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
37 citations
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June 2011 in “Pediatrics in Review” Puberty is driven by hormonal changes, mainly influenced by genetics, nutrition, and body fat.
37 citations
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September 2002 in “Acta pædiatrica” A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.
35 citations
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May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
31 citations
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January 2018 in “Pediatric annals” Early adrenal gland maturation in young children can be normal, but other serious conditions should be ruled out first.
30 citations
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December 2001 in “Journal of The European Academy of Dermatology and Venereology” Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
30 citations
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January 1998 in “Dermatology” Birth control pills and cyproterone acetate can help treat acne in women, especially when linked to hormonal issues.
29 citations
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September 1986 in “Journal of the American Veterinary Medical Association” The cat had a pituitary tumor causing hormone imbalance and related health issues.
28 citations
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July 2017 in “Journal of Endocrinological Investigation” Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.