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GlossaryAdrenalectomy

surgical removal of one or both adrenal glands

Adrenalectomy is a surgical procedure to remove one or both of the adrenal glands, which are small glands located on top of each kidney. These glands produce hormones such as cortisol, adrenaline, and aldosterone, which are crucial for regulating metabolism, immune response, blood pressure, and stress response. This surgery is typically performed to treat conditions like adrenal tumors, Cushing's syndrome, or pheochromocytoma.

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Stimulating Effect of Adrenalectomy on Hair Growth and Melanin Deposition in Black Rats Fed Diets Adequate and Deficient in the Filtrate Factors of Vitamin B1

research STIMULATING EFFECT OF ADRENALECTOMY ON HAIR GROWTH AND MELANIN DEPOSITION IN BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

34 citations , January 1943 in “Endocrinology”

Adrenalectomy boosts hair growth and melanin in black rats, even with vitamin B¹ deficiency.

The Effects of Synthetic and Natural Hormones of the Adrenal Cortex on Melanin Deposition in Adrenalectomized Black Rats Fed Diets Adequate and Deficient in Vitamin B1

research THE EFFECTS OF THE SYNTHETIC AND NATURAL HORMONE OF THE ADRENAL CORTEX ON MELANIN DEPOSITION IN ADRENALECTOMIZED BLACK RATS FED DIETS ADEQUATE AND DEFICIENT IN THE FILTRATE FACTORS OF VITAMIN B¹

27 citations , October 1945 in “Endocrinology”

Synthetic hormone treatment reduces melanin and hair growth in rats.

research Adrenocorticotropic Hormone (ACTH) But Not Alpha-Melanocyte Stimulating Hormone (a-MSH) as a Mediator of Adrenalectomy Induced Hair Growth in Mink

16 citations , April 1998 in “Journal of Investigative Dermatology”

ACTH promotes hair growth in mink, but α-MSH does not.

research Replacement with GABAergic steroid precursors restores the acute ethanol withdrawal profile in adrenalectomy/gonadectomy mice

12 citations , December 2009 in “Neuroscience”

GABAergic steroid precursors reduce ethanol withdrawal symptoms in certain mice.

research THE EFFECT OF ADRENALECTOMY AND ADRENOCORTICAL HORMONES ON THE HAIR GROWTH CYCLE IN THE RABBIT AND RAT

12 citations , July 1958 in “Journal of Endocrinology”

Cortisone suppresses hair regrowth, especially undercoat hair, while adrenalectomy affects hair growth differently in rabbits and rats.

research Ectopic Adrenal Rests in Congenital Adrenal Hyperplasia as a Cause of Androgen Excess after Adrenalectomy Detected by Pelvic Venous Sampling

7 citations , January 2013 in “Hormone Research in Paediatrics”

Ectopic adrenal rests can cause androgen excess after adrenalectomy and may need targeted surgery.

research Prevalence of Systemic Hypertension and Control of Systolic Blood Pressure in a Cohort of 14 Dogs with Adrenal-Dependent Hypercortisolism during the First Year of Trilostane Treatment or after Adrenalectomy

February 2024 in “Animals”

Most dogs with adrenal-dependent hypercortisolism had normal blood pressure after one year of treatment or surgery.

research Can Extra Adrenal Cortisol Secretion Occur in an Adrenalectomized Patient?

May 2021 in “Journal of the Endocrine Society”

A patient produced cortisol after adrenalectomy, possibly due to residual tissue or other body parts making steroids.

research Bilateral adrenalectomy induces early onset of summer fur growth in mink (Mustela vison)

5 citations , June 1995 in “Comparative biochemistry and physiology. Part C. Comparative pharmacology and toxicology/Comparative biochemistry and physiology. C. Comparative pharmacology and toxicology”

Removing mink's adrenal glands causes their summer fur to grow earlier.

research Laparoscopic adrenalectomy – a cure for male pattern baldness

January 2007 in “Annals of The Royal College of Surgeons of England”

Removing a hormone-producing adrenal tumor can stop hair loss in women with high testosterone levels.

research Stimulating effect of adrenalectomy on hair growth and melanin deposition in black rats fed diets adequate and deficient in the filtrate factors of vitamin B. With a note on effect of diet on post-operative survival.

January 1943

research HAIR-LOSS AS DEFICIENCY TEST OF MEDULLECTOMY IN RATS

96 citations , January 1940 in “Journal of Endocrinology”

Complete adrenal removal causes more hair loss in rats than partial removal.

research Hyperadrenocorticism associated with adrenocortical tumor or nodular hyperplasia of the adrenal gland in ferrets: 50 cases (1987-1991)

83 citations , July 1993 in “Journal of the American Veterinary Medical Association”

Diagnosis of adrenal issues in ferrets should use symptoms, ultrasound, and surgery, not ACTH tests.

research Virilizing Adrenocortical Oncocytoma in a Child: A Case Report

32 citations , January 2010 in “Journal of Korean Medical Science”

A rare adrenal tumor in a 14-year-old girl caused male-like symptoms and was successfully removed.

research Ethanol‐induced elevation of 3α‐hydroxy‐5α‐pregnan‐20‐one does not modulate motor incoordination in rats

26 citations , August 2004 in “Alcoholism Clinical and Experimental Research”

Ethanol-induced motor incoordination in rats is not affected by increased neuroactive steroids.

research Co-secretion of testosterone and cortisol by a functional adrenocortical oncocytoma

16 citations , August 2007 in “Histopathology”

A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.

research The role of the adrenal glands in regulating onset of winter fur growth in mink (Mustela vison)

16 citations , July 1992 in “The journal of experimental zoology/Journal of experimental zoology”

Adrenal glands delay the start of winter fur growth in mink.

research Role of prolactin in regulating the onset of winter fur growth in mink (Mustela vison): A reconsideration

12 citations , September 1999 in “The journal of experimental zoology/Journal of experimental zoology”

Prolactin levels do not control the start of winter fur growth in mink.

research Case Report: A Virilizing Adrenal Oncocytoma

6 citations , March 2021 in “Frontiers in surgery”

A woman's symptoms of increased body hair and testosterone were caused by a rare adrenal tumor, which was removed successfully.

research Adrenal Mass in a 70-Year-Old Woman

1 citations , July 2022 in “Case reports in endocrinology”

A 70-year-old woman with a malignant adrenal tumor improved after surgery and radiotherapy.

research Aldosterone- and cortisol-cosecreting adrenal adenoma, ovarian hyperthecosis and breast cancer

1 citations , September 2020 in “Endocrinology, Diabetes & Metabolism Case Reports”

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

research Adrenal myelolipoma: A rare entity

1 citations , December 2019 in “Medical Journal of Dr D Y Patil Vidyapeeth”

A rare adrenal gland tumor can cause unusual symptoms due to hormone changes.

research Ausgeprägte Virilisierung in der Postmenopause - eine Falldarstellung

1 citations , March 2005 in “Zentralblatt für Gynäkologie”

A postmenopausal woman had high testosterone from her right adrenal gland, leading to recommended surgery.

research P-017 CUSHING'S SYNDROME DUE TO PRIMARY BILATERAL MACRONODULAR ADRENAL HYPERPLASIA AND METACRONOUS PHEOCHROMOCYTOMA

January 2026 in “JCEM Case Reports”

A rare case of Cushing's syndrome and pheochromocytoma requires careful re-evaluation to avoid complications.

research A rare case of Cushing syndrome with virilization

July 2025

A 10-year-old girl's symptoms improved after surgery to remove a benign adrenal tumor.

research SAT320 Cyclic Cushing Syndrome Caused By An ACTH-Producing Pheochromocytoma

October 2023 in “Journal of the Endocrine Society”

A woman's cyclic Cushing syndrome was caused by a tumor in her adrenal gland that produced ACTH.

research A Very Rare Reason for Hyperandrogenism: Adrenal Tumor Case

March 2023 in “Bagcılar medical bulletin”

A young woman had a rare tumor causing high male hormone levels and symptoms like excessive hair and acne. After removing the tumor, her hormone levels returned to normal. Early diagnosis is important.

A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

research A Unique Case of Isolated Dehydroepiandrosterone-Sulfate Secreting Adrenocortical Carcinoma: A Case Report with Review of the Literature

October 2021 in “Acta Scientific Medical Sciences”

A woman was diagnosed with a rare adrenal gland cancer that did not show usual hormone-related symptoms.

research ANDROGEN AND CORTISOL SECRETING ADRENOCORTICAL ONCOCYTOMA WITTH UNCERTAIN MALIGNANT POTENTIAL

July 2019 in “Journal of the ASEAN Federation of Endocrine Societies”

The woman had a rare adrenal tumor removed, and she recovered well with no signs of the tumor returning.

research Virilizing adrenocortical oncocytoma in a toddler

August 2017 in “Journal of pediatric surgery case reports”

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.