7 citations
,
May 2014 in “Iranian Red Crescent medical journal” Laser hair removal is effective for hirsutism when combined with treatment for the underlying causes.
October 2024 in “Journal of the Endocrine Society” Hirsutism in young girls can have causes other than PCOS, so diagnoses should be reassessed if treatments don't work.
Melampus might have cured Proetus' daughters, who possibly had ergotism or Cushing's syndrome, using the herb Helleborus niger, but a mix of factors could have caused their symptoms.
293 citations
,
November 2005 in “Trends in Immunology” Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
248 citations
,
December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
199 citations
,
July 2007 in “General and Comparative Endocrinology” Hair cortisol can reliably indicate chronic stress in cats and dogs.
123 citations
,
May 2009 in “Journal of Neuroscience” In late pregnancy, allopregnanolone reduces stress responses in rats by affecting brain chemicals.
101 citations
,
January 2014 in “Journal of Visualized Experiments” The method effectively measures long-term stress levels using hair samples.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
88 citations
,
May 2020 in “Clinical therapeutics” Stress can worsen skin diseases by affecting immune cells, hormones, and neurotransmitters in the skin.
83 citations
,
July 2004 in “Pharmacology Biochemistry and Behavior” Higher 3α,5α-THP levels in the brain may reduce depression in pregnant rats.
81 citations
,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
80 citations
,
January 2011 in “Clinical Chemistry and Laboratory Medicine (CCLM)” Hair cortisol levels can reflect salivary cortisol levels in humans.
76 citations
,
October 2011 in “Clinica Chimica Acta” Hot water and UV exposure reduce hair cortisol levels, with the back of the head showing the most consistent levels.
69 citations
,
May 2009 in “Journal of Investigative Dermatology” Stress might contribute to hair loss in alopecia areata.
61 citations
,
September 2010 in “Journal of Dermatological Science” Stress hormones and autoimmune reactions can cause hair loss.
61 citations
,
March 2003 in “American Journal Of Pathology” Stress can cause hair loss and skin issues by affecting hair growth cycles.
56 citations
,
November 2010 in “Pigment Cell & Melanoma Research” Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.
50 citations
,
July 2018 in “Psychoneuroendocrinology” Hair cortisol can indicate long-term stress levels, but hair growth rate differences may affect accuracy.
50 citations
,
February 2007 in “Clinical obstetrics and gynecology” Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.
46 citations
,
October 2012 in “Seminars in reproductive medicine” Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.
42 citations
,
January 2006 in “Obstetrical & Gynecological Survey” The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.
38 citations
,
April 2018 in “Psychopharmacology/Psychopharmacologia” Blocking CRF-R1 can reduce alcohol intake in stressed mice.
35 citations
,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
26 citations
,
January 1982 in “Hormone Research” Normal androgen levels need ACTH, and different mechanisms control adrenarche and gonadarche.
24 citations
,
October 2018 in “Addiction Biology” Alcohol dependence affects stress hormone levels more than childhood maltreatment.
23 citations
,
January 2016 in “Brazilian Journal of Psychiatry” First-episode psychosis patients have higher hair cortisol levels, indicating early stress response issues.
22 citations
,
August 2011 in “Endocrine Practice” Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.
22 citations
,
November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” Hair growth and health are influenced by stress and hormones.
20 citations
,
November 2019 in “Biomolecules” Finasteride reduces response to stress and rewards, affecting behavior and mental health.