research Molecular mechanism of ligand recognition and activation of lysophosphatidic acid receptor LPAR6
LPAR6 has a unique way of binding and activating, which helps in designing treatments for hair loss and cancer.
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research The beneficial effects of chick embryo extract preconditioning on hair follicle stem cells: A promising strategy to generate Schwann cells
Chick embryo extract helps rat hair follicle stem cells potentially turn into Schwann cells, important for the nervous system.
research Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets
Misbehaving hair follicle stem cells can cause hair loss and offer new treatment options.
research Brown Adipose Tissue and Novel Management Strategies for Polycystic Ovary Syndrome Therapy
Activating brown fat may help manage PCOS symptoms.
research Sympathetic Reinnervation of Intact and Upper Follicle Xenografts into BALB/c-nu/nu Mice
Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.
research Recent advances in the role of neuroregulation in skin wound healing
Neuroregulation is crucial for skin wound healing and can be targeted to improve recovery.
research Using the zebrafish lateral line to uncover novel mechanisms of action and prevention in drug-induced hair cell death
Zebrafish helped find new ways to prevent drug-induced hair cell death and potential treatments for hearing loss.
research Exogeneous metal ions as therapeutic agents in cardiovascular disease and their delivery strategies
Metal ions can help treat heart diseases by protecting cells and repairing tissues.
research Epigenetic regulation of 5α reductase-1 underlies adaptive plasticity of reproductive function and pubertal timing
Environmental factors affect reproductive traits by altering the SRD5A1 gene.
research Wounds and the Microbiota: The Healing Interplay Between Host and Microbial Communities
Balancing good and harmful microbes is key to healing chronic wounds.
research Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages
Touch dome keratinocytes in adult skin have traits of different skin cell types.
research Dermal white adipose tissue development and metabolism: The role of transcription factor Foxn1
Foxn1 is important for fat development, metabolism, and wound healing in skin.
research Brown adipose tissue in the form of innovative approach for polycystic ovary syndrome treatmentstill long time to reach clinical arena: a narrative review
Brown Adipose Tissue (BAT) could potentially treat Polycystic Ovary Syndrome (PCOS) by controlling energy balance and lipid homeostasis, but more human research is needed.
research Hair Follicle Stem Cells and Hair Regeneration
research Hair Follicle Stem Cells and Hair Regeneration
research Ornithine decarboxylase is upregulated by the androgen receptor in skeletal muscle and regulates myoblast proliferation
Androgens increase muscle mass by promoting myoblast growth through ornithine decarboxylase.
research Oral Minoxidil for Alopecia Treatment: Risks, Benefits, and Recommendations
Low-dose oral minoxidil can effectively promote hair growth but requires careful monitoring for safety.
research Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding
Specific mutations in a receptor cause facial abnormalities and hair loss.
research The Biological Actions of Dehydroepiandrosterone Involves Multiple Receptors
DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.
research Phytochemistry, pharmacological activity, and potential health benefits of Glycyrrhiza glabra
Licorice has many health benefits but should be used carefully due to possible side effects.
research Syndecan-1 Is Required to Maintain Intradermal Fat and Prevent Cold Stress
Syndecan-1 is essential for maintaining skin fat and preventing cold stress.
research In Search of New Therapeutics—Molecular Aspects of the PCOS Pathophysiology: Genetics, Hormones, Metabolism and Beyond
New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.
research Emerging Roles for Ion Channels in Ovarian Cancer: Pathomechanisms and Pharmacological Treatment
Ion channels play a key role in ovarian cancer growth and treatment resistance.
research Comprehensive Review of Perilla frutescens: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
Perilla frutescens is a versatile herb with health benefits and potential in food and industrial uses.
research Improving the treatment of bacterial infections caused by multidrug-resistant bacteria through drug repositioning
Using existing drugs for new purposes can effectively treat infections resistant to multiple antibiotics.
research Cell-Free Therapies: The Use of Cell Extracts to Mitigate Irradiation-Injured Salivary Glands
Cell extracts may effectively and safely repair radiation-damaged salivary glands.
research Polycystic ovary syndrome: a common reproductive syndrome with long-term metabolic consequences
Polycystic ovary syndrome increases the risk of diabetes, heart disease, and endometrial cancer, and requires early treatment to manage these risks.
research Roles of steroid receptors in the lung and COVID-19
Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.
research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications
Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.
research The Impact of Glucagon-like Peptide-1 Receptor Agonists on Erectile Function: Friend or Foe?
The effect of GLP-1 RAs on erectile function is unclear and needs more research.