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HaCaT-Conditioned Medium Supplemented with Small Molecule Inhibitors SB431542 and CHIR99021 and Growth Factor PDGF-AA Prevents the Dedifferentiation of Dermal Papilla Cells In Vitro

research HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro

7 citations , March 2021 in “Molecular Medicine Reports”

A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.

Effectiveness and Stability Test of Shallot Extract (Allium Cepa L.) Hair Tonic as a Hair Growth Stimulant

research UJI EFEKTIVITAS DAN STABILITAS HAIR TONIC EKSTRAK BAWANG MERAH (Allium cepa L.) SEBAGAI PERANGSANG PERTUMBUHAN RAMBUT

January 2024 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan”

The F2 hair tonic with shallot extract is effective and stable for hair growth.

Big Head? Bald Head! Skull Expansion: Alternative Model for the Primary Mechanism of Androgenetic Alopecia

research Big head? Bald head! Skull expansion: alternative model for the primary mechanism of AGA

8 citations , September 2008 in “Medical Hypotheses”

The paper suggests that hair loss might be caused by skull growth, not just DHT's effect on hair follicles, and calls for more research.

research Evaluation of oxidative stress markers in Androgenetic Alopecia Patients

December 2023 in “Benha Journal of Applied Sciences”

AGEs and their receptors play a significant role in hair loss by causing inflammation and oxidative stress.

research Inducible expression of gasdermin A3 in the epidermis causes epidermal hyperplasia and skin inflammation

12 citations , July 2015 in “Experimental Dermatology”

Gasdermin A3 overexpression in skin causes inflammation and hair loss.

research A Mouse Model for the Basal Transcription/DNA Repair Syndrome Trichothiodystrophy

188 citations , June 1998 in “Molecular cell”

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

research Ascorbigen Induces Dermal Papilla Cell Proliferation in Vitro , but Fails to Modulate Chemotherapy-Induced Alopecia in Vivo

2 citations , March 2013 in “Phytotherapy Research”

Ascorbigen increases hair cell growth in a lab setting but does not prevent hair loss from chemotherapy in mice.

research Mendelian Randomization Identifies CD25+ CD4+ Tregs and Plasma Proteins in Androgenetic Alopecia Pathogenesis

November 2025 in “Clinical Cosmetic and Investigational Dermatology”

Immune cells and plasma proteins are linked to hair loss, suggesting new treatment options.

research Polynucleotides as a novel therapeutic approach in androgenetic alopecia: an analysis of effectiveness and safety

February 2025 in “Archives of Dermatological Research”

Polynucleotides effectively promote hair regrowth in androgenetic alopecia without serious side effects.

research Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells

16 citations , January 2016 in “Annals of Dermatology”

Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.

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