Androgenetic Alopecia
October 2025
in “
Nature Reviews Disease Primers
”
Research cited in this study
227 / 227 results
research Technological Advances in Anti-Hair Loss and Hair Regrowth Cosmeceuticals: Mechanistic Breakthroughs and Industrial Prospects Driven by Multidisciplinary Collaborative Innovation
Collaboration and innovation are key to developing effective, safe hair loss treatments.
research Exosome Therapy for Androgenetic Alopecia: Balancing Potential with Standardization Challenges
research Anti-Androgen Therapy for the Treatment of Female Pattern Hair Loss: A Clinical Review of Current and Emerging Therapies
Oral and topical anti-androgens can help treat female hair loss, but have side effects.
research Summation and Recommendations for the Safe and Effective Use of Topical and Oral Minoxidil
Use minoxidil correctly and be aware of side effects for best hair loss treatment results.
research Uncovering the Genetic Architecture and Evolutionary Roots of Androgenetic Alopecia in African Men
Genetic predictions of baldness in Europeans don't apply well to African men.
research Innovative Strategies for the Discovery of New Drugs Against Androgenetic Alopecia
New drug strategies are needed for better hair loss treatments.
research Unhealthy Diet and Lifestyle Factors Linked to Female Androgenetic Alopecia: A Community-Based Study from Jidong, China
Unhealthy diet and lifestyle choices may increase the risk of hair loss in women.
research Glucagon-Like Peptide-1 Receptor Agonist Medications and Hair Loss: A Retrospective Cohort Study
GLP-1 RA medications may be linked to hair loss.
research Restoration of Hair Follicle Inductive Properties by Depletion of Senescent Cells
Removing senescent cells can improve hair growth and regeneration.
research Outcomes of Androgenetic Alopecia Treated with Dutasteride Mesotherapy: A Case Series
Dutasteride mesotherapy showed mixed results and is not recommended as a primary treatment for hair loss.
research Hair-Raising Costs: Evaluating Botulinum Toxin Treatment for Androgenetic Alopecia
Botulinum toxin is not effective or cost-efficient for treating male pattern baldness.
research Dutasteride for the Treatment of Androgenetic Alopecia: An Updated Review
Dutasteride works better than finasteride for hair loss and has mild, reversible side effects.
research Low-Dose Metformin and Profibrotic Signature in Central Centrifugal Cicatricial Alopecia
Low-dose metformin may help hair regrowth and reduce inflammation in CCCA.
research A Comprehensive Investigation of Biochemical Status in Patients with Telogen Effluvium: Analysis of Hb, Ferritin, Vitamin B12, Vitamin D, Thyroid Function Tests, Zinc, Copper, Biotin, and Selenium Levels
Telogen effluvium is linked to deficiencies in iron, vitamin B12, and thyroid function.
research Unique Presentations of Female Pattern Hair Loss Evident in Asian and Black Women
Hair loss patterns in Asian and Black women are unique and may affect treatment.
research Efficacy of Botulinum Toxin in Male Androgenetic Alopecia: A Triple-Blind, Randomized Clinical Trial
Botulinum toxin may help treat male pattern baldness.
research Hair Follicle Sulfotransferase Activity and Effectiveness of Oral Minoxidil in Androgenetic Alopecia
Low SULT activity in hair follicles leads to better response to oral minoxidil for hair loss.
research Trichoscopy of Frontal Fibrosing Alopecia in Caucasians: A Review
Trichoscopy helps diagnose frontal fibrosing alopecia in Caucasians, but more research is needed.
research Treatment of Insulin Resistance With Tirzepatide Leading to Improvement of Hair Loss
Tirzepatide may improve hair loss by reducing insulin resistance.
research The Impact of Monotherapies for Male Androgenetic Alopecia: A Network Meta-Analysis Study
"Dutasteride 0.5 mg daily is the most effective treatment for male hair loss."
research Factors Associated With Early-Onset Androgenetic Alopecia: A Scoping Review
Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.
research Efficacy and Safety of Low-Dose Oral Minoxidil in the Management of Androgenetic Alopecia
Low-dose oral minoxidil is effective and safe for treating hair loss in men and women.
research Efficacy and Safety of Combined Microneedling Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Microneedling combined with other treatments significantly improves hair growth in people with hair loss and is safe.
research Is Thyroid Dysfunction a Common Cause of Telogen Effluvium? A Retrospective Study
Hypothyroidism is often linked to the hair loss condition telogen effluvium.
research A Meta-Analysis Study on the Association Between Smoking and Male Pattern Hair Loss
Smoking increases the risk of male pattern hair loss.
research Comparative Effects of Monotherapy with Topical Minoxidil, Oral Finasteride, and Topical Finasteride in Postmenopausal Women with Pattern Hair Loss: A Retrospective Cohort Study
Oral finasteride seems more effective for hair loss in postmenopausal women, but more research is needed.
research Impact of Hair Transplantation on Quality of Life
Hair transplantation improves quality of life and reduces stress and anxiety.
research No-Shave Long Hair Follicular Unit Excision Using an All-Purpose Skin-Responsive Device
The new hair transplant technique is fast, effective, and satisfying for patients with different hair types.
research Trichoscopy – A Valuable Tool for Identifying Conditions Mimicking Androgenetic Alopecia
Trichoscopy helps tell apart other hair loss conditions from common hair loss.
research Complications With Follicular Unit Excision
FUE hair restoration is generally safe but can have complications, especially if done by untrained individuals.
research Local and Systemic Mechanisms That Control the Hair Follicle Stem Cell Niche
research Incorporation of Hair Follicles in 3D Bioprinted Models of Human Skin
3D bioprinting can now create skin with hair-like structures for medical use.
research Uncovering the Complex Relationship Between Balding, Testosterone, and Skin Cancers in Men
Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.
research Efficacy of Autologous Dermal Sheath Cup Cell Transplantation in Male and Female Pattern Hair Loss: A Single-Arm, Multi-Center, Phase III Equivalent Clinical Study
Transplanting one's own hair follicle cells can improve hair loss in men and women, and is particularly effective in women.
research Analysis of 72,469 UK Biobank Exomes Links Rare Variants to Male-Pattern Hair Loss
Rare genetic variants in five specific genes are linked to male-pattern hair loss but only account for a small part of the risk.
research Short Anagen Hair Syndrome: Association With Mono- and Biallelic Variants in WNT10A and a Genetic Overlap With Male Pattern Hair Loss
Some cases of short anagen hair syndrome are linked to specific genetic variations that are also connected to male pattern baldness.
research Efficacy and Safety of Combinational Therapy Using Topical Minoxidil and Microneedling for the Treatment of Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Using minoxidil with microneedling increases hair count for hair loss without serious side effects.
research Psychosocial Impact of Androgenetic Alopecia on Men: A Systematic Review and Meta-Analysis
Hair loss (androgenetic alopecia) mildly to moderately affects men's quality of life but not significantly their mental health.
research What Do We Know About Hair Growth Induced by Wounding and Its Therapeutic Applications?
Wounding may stimulate hair growth, but more research is needed to confirm the safety and effectiveness of related treatments.
research Beyond the Epidermal-Melanin-Unit: The Human Scalp Anagen Hair Bulb Is Home to Multiple Melanocyte Subpopulations of Variable Melanogenic Capacity
The human scalp hair bulb contains different types of melanocytes with varying abilities to produce melanin.
research Integrated Single-Cell Chromatin and Transcriptomic Analyses of Human Scalp Identify Gene-Regulatory Programs and Critical Cell Types for Hair and Skin Diseases
research Androgenetic Alopecia: An Update
Two drugs, finasteride and minoxidil, are approved for hair loss treatment, but new therapies are being developed.
research Platelet Rich Plasma Combination Therapies for Treatment of Androgenetic Alopecia: A Systematic Review
Combining platelet-rich plasma with other treatments may improve hair growth in people with hair loss, but more research is needed.
research Signaling by Senescent Melanocytes Hyperactivates Hair Growth
Senescent melanocytes can boost hair growth by activating hair stem cells.
research Male Pattern Hair Loss: Can Developmental Origins Explain the Pattern?
Male pattern hair loss may be linked to the developmental origins of hair follicles.
research Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs
More personalized and effective treatments for androgenetic alopecia are needed.
research Male-Pattern Hair Loss: Comprehensive Identification of the Associated Genes as a Basis for Understanding Pathophysiology
Male-pattern hair loss is largely influenced by genetics, with key genes identified.
research Assessment of Quality of Life and Self-Esteem in Male Patients With Androgenetic Alopecia Before and After Hair Transplantation
Hair transplantation significantly improves quality of life and self-esteem in men with hair loss.
research Mesotherapy With Dutasteride for Androgenetic Alopecia: A Concise Review of the Literature
The document concludes that injecting dutasteride into the skin (mesotherapy) can effectively treat common hair loss in both men and women.
research The AR/miR-221/IGF-1 Pathway Mediates the Pathogenesis of Androgenetic Alopecia
A specific pathway involving AR, miR-221, and IGF-1 plays a key role in causing common hair loss.
research The Association Between Sugar-Sweetened Beverages and Male Pattern Hair Loss in Young Men
Drinking lots of sugary drinks may increase the risk of hair loss in young men.
research Efficacy of Low-Dose Oral Minoxidil in the Management of Anticancer Therapy-Induced Alopecia in Patients With Breast Cancer: A Retrospective Cohort Study
Low-dose oral minoxidil combined with topical minoxidil improves hair growth in breast cancer patients with therapy-induced hair loss.
research Skin-On-A-Chip Strategies For Human Hair Follicle Regeneration
New technologies show promise for better hair regeneration and treatments.
research Activated Platelet Rich Plasma Versus Non-Activated Platelet Rich Plasma in the Treatment of Alopecia Areata
Activated and non-activated PRP are equally safe and effective for treating alopecia areata.
research Wound-Induced Hair Neogenesis: A Portal to the Development of New Therapies for Hair Loss and Wound Regeneration
Wound healing can potentially regrow hair and aid in hair loss treatments.
research Efficacy of Platelet-Rich Plasma in Asians With Androgenetic Alopecia: A Randomized Controlled Trial
research A Comprehensive Review of Microneedling as a Potential Treatment Option for Androgenetic Alopecia
research Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla
Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
research Hedgehog Signaling Reprograms Hair Follicle Niche Fibroblasts to a Hyper-Activated State
Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.
research The First Broad Replication Study of SNPs and a Pilot Genome-Wide Association Study for Androgenetic Alopecia in Asian Populations
Two specific genetic markers increase the risk of hair loss in Asian populations.
research Photobiomodulation Therapy With Different Wavebands for Hair Loss: A Systematic Review and Meta-Analysis
Light therapy with various colors helps treat hair loss.
research A Cross-Sectional Study of Male Balding Patterns in People of Color
The study found different balding patterns in men of color.
research Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model
Minoxidil-loaded hyaluronic acid microneedles can effectively increase hair growth and could be a promising treatment for hair loss.
research Prevalence of Female Pattern Hair Loss in Postmenopausal Women: A Cross-Sectional Study
Over half of postmenopausal women experience hair loss, with severity increasing with age, time since menopause, and higher body mass index.
research Androgen Receptor-Mediated Paracrine Signaling Induces Regression of Blood Vessels in the Dermal Papilla in Androgenetic Alopecia
Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.
research Long-Term Effectiveness and Safety of Dutasteride Versus Finasteride in Patients With Male Androgenic Alopecia in South Korea: A Multicentre Chart Review Study
Dutasteride is more effective than finasteride for long-term hair growth in men with androgenic alopecia.
research Microneedling and Its Use in Hair Loss Disorders: A Systematic Review
Microneedling helps with hair loss, especially with 5% minoxidil, but more high-quality research is needed.
research The Inflammatory Component of Androgenetic Alopecia
Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.
research Efficacy and Safety of Topical Finasteride Spray Solution for Male Androgenetic Alopecia: A Phase III, Randomized, Controlled Clinical Trial
Topical finasteride is an effective and safer treatment for male hair loss.
research Retrograde Androgenetic Alopecia
research Perifollicular Inflammation and Follicular Spongiosis in Androgenetic Alopecia
Hair loss in both Androgenetic Alopecia and Alopecia Areata is often accompanied by inflammation around hair follicles, but the location and severity of this inflammation varies.
research Health-Related Quality of Life, Depression, and Self-Esteem in Patients With Androgenetic Alopecia
Androgenetic alopecia negatively affects quality of life and self-esteem, especially in women, but not depression.
research The 'Bald' Phenotype (Androgenetic Alopecia) Is Caused by the High Glycemic, High Cholesterol, and Low Mineral 'Western Diet'
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.
research The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma on Hair Density and Diameter in Androgenetic Alopecia: A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB-Approved Study
Higher cell number PRP improves hair density and diameter more than lower cell number PRP.
research Long Hair Follicular Unit Excision: Personal Experience
Long hair follicular unit excision is effective for hair transplants, providing quick, natural-looking results with less pain but needs more time, staff, and skill.
research Hair Transplantation: Basic Overview
Hair transplantation can effectively restore hair in balding areas.
research Preview Long Hair Follicular Unit Excision: An Up-And-Coming Technique
Long hair FUE, a hair transplant without shaving, is becoming more popular and surgeons should learn it.
research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation
Fat under the skin releases HGF which helps hair grow and gain color.
research Suicidality and Psychological Adverse Events in Patients Treated with Finasteride
research Investigation of Suicidality and Psychological Adverse Events in Patients Treated With Finasteride
Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.
research The Inflammatory Aspect of Male and Female Pattern Hair Loss
Inflammation affects hair loss; anti-inflammatory treatments may help.
research Female Pattern Hair Loss in Men: A Distinct Clinical Variant of Androgenetic Alopecia
Men can experience female pattern hair loss, needing different treatments.
research Microneedling: A Novel Therapeutic Approach for Androgenetic Alopecia, A Review of Literature
Microneedling may help hair loss, but needs more research.
research Efficacy and Safety of Oral Minoxidil in Female Androgenetic Alopecia
Oral minoxidil improves hair density in women with androgenetic alopecia, with mild side effects.
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
research Evaluation of Platelet-Rich Plasma as a Treatment for Androgenetic Alopecia: A Randomized Controlled Trial
PRP treatment improves hair density and thickness for alopecia, but needs more research.
research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
research Cross-Sectional Quality of Life Assessment in Patients with Androgenetic Alopecia
Hair loss lowers quality of life, causing embarrassment, frustration, and sexual rejection.
research Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells
Scientists created human skin with hair from stem cells, which could help treat hair loss and skin conditions.
research The Utility of Platelet-Rich Plasma for the Treatment of Alopecia
PRP can help regrow hair in people with alopecia.
research Innovations Hair Restoration Surgeons Have Made to Adapt to the Challenges of Follicular Unit Excision
Hair restoration surgeons have improved follicular unit excision (hair transplant method) by using innovative tools and techniques, reducing hair damage and increasing success rates.
research The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism
Botulinum toxin injections may help treat hair loss by blocking harmful secretion in hair follicles.
research Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss Using Dermal Sheath Cup Cells: A Randomized Placebo-Controlled Double-Blinded Dose-Finding Clinical Study
DSC cell injections significantly improved hair density and diameter, showing potential as a hair loss treatment.
research Fibrosing Alopecia in a Pattern Distribution
Fibrosing alopecia in a pattern distribution is a hair loss condition often confused with other types, requiring early treatment but usually not resulting in significant hair regrowth.
research Skin and Hair Abnormalities of Cantu Syndrome: A Congenital Hypertrichosis Due to a Genetic Alteration Mimicking the Pharmacological Effect of Minoxidil
Cantu syndrome, which causes excessive hair growth and skin issues, is due to a mutation in the ABCC9 gene, and understanding this could help develop new treatments for hair diseases.
research The Role of Family History and Its Influence on the Onset Time in Female Pattern Hair Loss
Family history, especially on the mother's side, increases the risk of female pattern hair loss.
research Female Androgenetic Alopecia: An Update on Diagnosis and Management
FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.
research Contemporary Management of Alopecia: A Systematic Review and Meta-Analysis for Surgeons
research Pediatric Androgenetic Alopecia: A Review
Early diagnosis and treatment, like topical minoxidil, can prevent hair loss in children.
research Deciphering the Molecular Morphology of the Human Hair Cycle: Wnt Signalling During the Telogen–Anagen Transformation
Wnt signaling is important for the change from the resting phase to the growth phase in human hair cycles.
research Assessment of Quality of Life and Treatment Outcomes of Patients With Persistent Postchemotherapy Alopecia
Hair regrowth treatments had modest benefits for patients with long-term hair loss after chemotherapy.
research Female Pattern Hair Loss and Androgen Excess: A Report From the Multidisciplinary Androgen Excess and PCOS Committee
Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.
research The Relationship Between Self-Esteem and Hair Transplantation Satisfaction in Male Androgenetic Alopecia Patients
Hair transplant boosts self-esteem and appearance satisfaction, especially in those with high self-esteem.
research Dissection of Genetic Variation and Evidence for Pleiotropy in Male Pattern Baldness
Male pattern baldness is mostly inherited, involves many genes, and is linked to other traits like early puberty and strong bones.
research Tissue Engineering of Human Hair Follicles Using a Biomimetic Developmental Approach
Researchers created human hair follicles using a new method that could help treat hair loss.
research Androgens in Women: Role in Androgen-Mediated Cutaneous Disorders
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Platelet-Rich Plasma for Androgenetic Alopecia: A Review of the Literature and Proposed Treatment Protocol
PRP shows promise for hair loss treatment, with three initial monthly injections and maintenance every 3-6 months.
research Efficacy and Safety of Low-Level Light Therapy for Androgenetic Alopecia: A 24-Week, Randomized, Double-Blind, Self-Comparison, Sham Device-Controlled Trial
Low-level light therapy safely improves hair coverage, thickness, and count in androgenetic alopecia patients.
research Endocrine Therapy-Induced Alopecia in Patients With Breast Cancer
Hair loss from hormone therapy in breast cancer patients can be improved with minoxidil treatment.
research Review of Quality of Life Studies in Women with Alopecia
Alopecia significantly lowers women's quality of life, with psychological and social challenges, highlighting the importance of early treatment and support.
research 5α-Reductase Isozymes and Aromatase mRNA Levels in Plucked Hair from Young Women with Female Pattern Hair Loss
Higher enzyme levels found in women with hair loss, suggesting hormone imbalance.
research Mediterranean Diet: Fresh Herbs And Fresh Vegetables Decrease The Risk Of Androgenetic Alopecia In Males
Mediterranean diet with fresh herbs and vegetables lowers male hair loss risk.
research GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk
Researchers found 71 genetic regions linked to male pattern baldness, which account for 38% of its genetic risk.
research Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
AGA linked to inflammation, stress, fibrosis, and disturbed hair follicle stem cells.
research Focal Atrichia: A Diagnostic Clue in Female Pattern Hair Loss
Focal atrichia helps diagnose female pattern hair loss.
research Androgens and Androgen Receptor Action in Skin and Hair Follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
research Alopecia and the Metabolic Syndrome
Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.
research A Preliminary Study on Topical Cetirizine in the Therapeutic Management of Androgenetic Alopecia
Topical cetirizine improves hair density and thickness in androgenetic alopecia, but more research is needed.
research The Combination of Overweight and Smoking Increases the Severity of Androgenetic Alopecia
Overweight smokers have worse hair loss.
research Genetics and Other Factors in the Etiology of Female Pattern Hair Loss
Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis
Minoxidil, finasteride, and low-level laser light therapy effectively treat hair loss.
research Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness
Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.
research Genetic Prediction of Male Pattern Baldness
Genetic factors can help predict male pattern baldness risk.
research Frequency, Severity, and Related Factors of Androgenetic Alopecia in Dermatology Outpatient Clinic: Hospital-Based Cross-Sectional Study in Turkey
AGA more common in men, increases with age, linked to family history, hypertension, dyslipidemia, and smoking.
research Interventions for Female Pattern Hair Loss
Topical minoxidil improves female pattern hair loss, finasteride not effective, laser devices show mixed results.
research Stress-Induced Premature Senescence of Dermal Papilla Cells Compromises Hair Follicle Epithelial-Mesenchymal Interaction
Stress can cause early aging in certain skin cells, leading to problems with hair growth.
research Male Pattern Baldness and Risk of Incident Skin Cancer in a Cohort of Men
Men with male pattern baldness have a higher risk of certain skin cancers, especially on the scalp.
research A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features
Genetic factors influence hair traits like shape, color, and greying in Latin Americans.
research Classifications of Patterned Hair Loss: A Review
Different types of hair loss need specific treatments, and while many classification systems exist, each has its flaws; more research is needed to refine these systems and treatments.
research Topical Minoxidil: Systematic Review and Meta-Analysis of Its Efficacy in Androgenetic Alopecia
Topical minoxidil significantly increases hair growth in androgenetic alopecia but only some patients see cosmetically acceptable results.
research Oral Finasteride Presents With Sexual-Unrelated Withdrawal in Long-Term Treated Androgenic Alopecia in Men
Most men stopped using the hair loss treatment not because of sexual side effects, but because they didn't see positive results.
research A Guide to Studying Human Hair Follicle Cycling In Vivo
The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.
research Persistent Sexual Dysfunction and Suicidal Ideation in Young Men Treated with Low-Dose Finasteride: A Pharmacovigilance Study
Low-dose finasteride may cause lasting sexual dysfunction and suicidal thoughts in young men.
research Enhancing Hair Follicle Regeneration by Nonablative Fractional Laser: Assessment of Irradiation Parameters and Tissue Response
Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
research Oxidative Stress-Associated Senescence in Dermal Papilla Cells of Men with Androgenetic Alopecia
Oxidative stress affects hair loss in men with androgenetic alopecia.
research Promising Alternative Clinical Uses of Prostaglandin F2α Analogs: Beyond the Eyelashes
Prostaglandin F2α analogs show promise for treating certain types of hair loss but need more research for other skin conditions.
research Visible Red Light Enhances Physiological Anagen Entry In Vivo And Has Direct And Indirect Stimulatory Effects In Vitro
Red light promotes hair growth by directly stimulating hair cells and improving cell communication.
research Pathologic Diagnosis of Central Centrifugal Cicatricial Alopecia on Horizontal Sections
Horizontal sections of scalp biopsies are good for diagnosing Central Centrifugal Cicatricial Alopecia and help customize treatment.
research FGF5 Is a Crucial Regulator of Hair Length in Humans
FGF5 gene mutations cause unusually long eyelashes by affecting hair growth regulation.
research Destruction of the Arrector Pili Muscle and Fat Infiltration in Androgenic Alopecia
Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.
research A Randomized, Active- and Placebo-Controlled Study of the Efficacy and Safety of Different Doses of Dutasteride Versus Placebo and Finasteride in the Treatment of Male Subjects with Androgenetic Alopecia
Dutasteride 0.5 mg works better than finasteride and placebo for increasing hair in men with hair loss.
research Androgenetic Alopecia, Metabolic Syndrome, and Insulin Resistance: Is There Any Association? A Case-Control Study
Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.
research Novel Enzymatic Assay Predicts Minoxidil Response in the Treatment of Androgenetic Alopecia
New test predicts if hair loss treatment will work.
research Organic Causes of Erectile Dysfunction in Men Under 40
Many men under 40 with erectile dysfunction have organic causes like vascular issues, medication side effects, or hormonal problems.
research Microenvironmental Reprogramming by Three-Dimensional Culture Enables Dermal Papilla Cells to Induce De Novo Human Hair-Follicle Growth
Growing human skin cells in a 3D environment can stimulate new hair growth.
research Genetic Variants at 20p11 Confer Risk to Androgenetic Alopecia in the Chinese Han Population
Genetic variants at 20p11 increase baldness risk in Chinese Han people.
research Low-Level Laser Therapy for Treatment of Hair Loss
Low-Level Laser Therapy is effective and safe for hair growth with minimal side effects.
research Female Pattern Alopecia: Current Perspectives
Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.
research Evidence for a Polygenic Contribution to Androgenetic Alopecia
Hair loss risk is influenced by multiple genes.
research Quality of Life in Women with Female Pattern Hair Loss and the Impact of Topical Minoxidil Treatment
Minoxidil improves quality of life for women with hair loss.
research Androgenetic Alopecia: Identification Of Four Genetic Risk Loci And Evidence For The Contribution Of WNT Signaling To Its Etiology
Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.
research Vellus Hairs in the Frontal Scalp in Early Female Pattern Hair Loss
More vellus hairs in frontal scalp indicate early female pattern hair loss.
research Factors Associated With Female Pattern Hair Loss And Its Prevalence In Taiwanese Women: A Community-Based Survey
FPHL common in Taiwanese women; risk factors include BMI, high glucose, early puberty, fewer childbirths, oral contraceptives, and UV exposure.
research Pattern Hair Loss in Men: Diagnosis, Genetic Link, Clinical Features, and Treatments
Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.
research Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth
Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
research Six Novel Susceptibility Loci for Early-Onset Androgenetic Alopecia and Their Unexpected Association with Common Diseases
Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.
research Dermoscopy-Guided Scalp Biopsy in Cicatricial Alopecia
Using dermoscopy to guide scalp biopsies is an effective way to diagnose cicatricial alopecia.
research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Hair and Scalp Dermatoscopy
Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.
research Selected Variants of the Steroid-5-Alpha-Reductase Isoforms SRD5A1 and SRD5A2 and the Sex Steroid Hormone Receptors ESR1, ESR2, and PGR: No Association with Female Pattern Hair Loss Identified
No link found between specific genes and female pattern hair loss.
research Hair Follicle Stem Cell Differentiation Is Inhibited Through Cross-Talk Between Wnt/β-Catenin and Androgen Signaling in Dermal Papilla Cells From Patients With Androgenetic Alopecia
Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.
research Susceptibility Variants on Chromosome 7p21.1 Suggest HDAC9 as a New Candidate Gene for Male-Pattern Baldness
A gene called HDAC9 might be a new factor in male-pattern baldness.
research Dihydrotestosterone-Inducible IL-6 Inhibits Elongation of Human Hair Shafts by Suppressing Matrix Cell Proliferation and Promotes Regression of Hair Follicles in Mice
IL-6 contributes to hair loss by shortening the growth phase and causing hair follicles to regress.
research A Randomized Double-Blind Placebo-Controlled Pilot Study to Assess the Efficacy of a 24-Week Topical Treatment by Latanoprost 0.1% on Hair Growth and Pigmentation in Healthy Volunteers with Androgenetic Alopecia
Latanoprost 0.1% may effectively treat hair loss.
research Dermoscopy of Scalp Tumors: A Multi-Center Study Conducted by the International Dermoscopy Society
The study concluded that scalp tumors show different patterns based on age, gender, and tumor thickness, and emphasized the importance of early detection and scalp examinations.
research Evidence of Increased DNA Methylation of the Androgen Receptor Gene in Occipital Hair Follicles from Men with Androgenetic Alopecia
Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.
research Oral Finasteride Improved the Quality of Life of Androgenetic Alopecia Patients
Finasteride helps hair loss patients' quality of life.
research S1 Guideline for Diagnostic Evaluation in Androgenetic Alopecia in Men, Women, and Adolescents
Guidelines for diagnosing common hair loss include detailed history, clinical examination, and various diagnostic techniques.
research Association of Androgenetic Alopecia with Metabolic Syndrome in Men: A Community-Based Survey
Balding men, especially young ones, may have higher risk of heart issues and diabetes; check cholesterol levels.
research Female Pattern Hair Loss in Complete Androgen Insensitivity Syndrome
Hair loss in women may have causes other than hormones.
research Practical Guidelines for Evaluation of Loose Anagen Hair Syndrome
Loose anagen hair syndrome, often affecting young girls, can be diagnosed with a hair-pull test and usually gets better on its own, but severe cases may need treatment.
research Androgenic Alopecia and Insulin Resistance: Are They Really Related?
There is no significant link between male pattern baldness and insulin resistance.
research Prevalence and Types of Androgenetic Alopecia in Shanghai, China: A Community-Based Study
Chinese men have lower AGA rates than Caucasians, with type III vertex most common; family history is important.
research The Hair Follicle as a Dynamic Mini-Organ
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Surgical Complications In Hair Transplantation: A Series Of 533 Procedures
Successful hair transplants need good communication, careful planning, skilled surgery, and proper aftercare.
research Hair Evaluation Methods: Merits and Demerits
Different hair evaluation methods have their own pros and cons, and using multiple methods together is best for accurate hair loss diagnosis and tracking.
research Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects
58% of men aged 30-50 have hair loss, with severity increasing with age.
research Susceptibility Variants for Male-Pattern Baldness on Chromosome 20p11
research Male-Pattern Baldness Susceptibility Locus at 20p11
Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.
research Human Hair Follicles Contain Two Forms of ATP-Sensitive Potassium Channels, Only One Sensitive to Minoxidil
One minoxidil-sensitive potassium channel exists in human hair follicles.
research Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated With p16INK4a Expression
Balding cells age faster due to stress, suggesting stress-targeting treatments for hair loss.
research Androgenetic Alopecia: Clinical Features, Classification, and Treatments
Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.
research A New Classification of Pattern Hair Loss That Is Universal for Men and Women: Basic and Specific (BASP) Classification
The BASP classification is a detailed and accurate way to categorize hair loss in both men and women.
research Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells
Adenosine may promote hair growth by increasing FGF-7 levels in dermal papilla cells.
research Dermatologic Manifestations of Polycystic Ovary Syndrome
Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.
research Human Scalp Hair Follicles Are Both a Target and a Source of Prolactin, Which Serves as an Autocrine and/or Paracrine Promoter of Apoptosis-Driven Hair Follicle Regression
Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.
research Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells
Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
research Prevalence of Male and Female Pattern Hair Loss in Maryborough
Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.
research Macrophage-Stimulating Protein Promotes Hair Growth Ex Vivo and Induces Anagen from Telogen Stage Hair Follicles In Vivo
Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Genetic Basis of Male Pattern Baldness
Male pattern baldness is largely genetic, linked to the androgen receptor gene, and may relate to certain health issues.
research Androgenetic Alopecia in Men Aged 40-69 Years: Prevalence and Risk Factors
Hair loss increases with age; alcohol raises risk, more female partners lowers it.
research Morphological Approach to Hair Disorders
Accurate clinical, histological, and genetic methods are key for understanding and treating hair disorders.
research Analysis of Genetic Polymorphisms of Steroid 5α-Reductase Type 1 and 2 Genes in Korean Men with Androgenetic Alopecia
Gene differences may affect baldness treatment response in Korean men.
research Is Androgenetic Alopecia a Photoaggravated Dermatosis?
Sunlight worsens hair loss; protect scalp.
research A Random Study of Asian Male Androgenetic Alopecia in Bangkok, Thailand
Male pattern baldness affects 38.52% of Asian men in Bangkok, increasing with age and influenced by genes and environment.
research Follicular Unit Extraction: Minimally Invasive Surgery for Hair Transplantation
Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.
research Hormonal Interaction And Hair Growth
Hormones, especially DHT, affect hair loss and growth, and targeting specific enzymes may help treat hair loss.
research Steroid Sulfatase in the Human Hair Follicle Concentrates in the Dermal Papilla
Steroid sulfatase in hair follicles may be a target for treating hair loss.
research Osteopontin Gene Is Expressed in the Dermal Papilla of Pelage Follicles in a Hair-Cycle-Dependent Manner
The osteopontin gene is active in a specific part of rat hair follicles during a certain hair growth phase and might affect hair cycle and diseases.
research Female Pattern Hair Loss
Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.
research Possible Mechanisms of Miniaturization During Androgenetic Alopecia or Pattern Hair Loss
Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.
research Animal Models for Male Pattern (Androgenetic) Alopecia
The stump-tailed macaque is a good model for studying human hair loss, but it's expensive and hard to find, while rodent models are promising for understanding hair growth and finding new treatments.
research The Prevalence and Types of Androgenetic Alopecia in Korean Men and Women
AGA more common in men, Koreans have lower rates and unique patterns.
research The Psychology of Hair Loss and Its Implications for Patient Care
Hair loss can significantly affect a person's self-esteem and body image, especially in young people, those who value their looks highly, and women.
research Hair Density, Hair Diameter, and the Prevalence of Female Pattern Hair Loss
FPHL affects hair density and diameter, causing visible hair loss in older women.
research Fibrosing Alopecia in a Pattern Distribution
Some people with pattern hair loss may also have scalp inflammation and scarring similar to lichen planopilaris.
research Male-Pattern Hair Loss in Norwegian Men: A Community-Based Study
Hair loss common in Norwegian men, affecting self-esteem and life quality.
research The Biology of Hair Follicles
Hair follicle biology advancements may lead to better hair growth disorder treatments.
research Distribution of Human Hair in Follicular Units
The research found that for a typical hair density, about 11 square centimeters of donor scalp is needed to get 800 hair grafts for transplantation.
research Finasteride in the Treatment of Men with Androgenetic Alopecia
Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.
research Genetic Analysis of Male Pattern Baldness and the 5α-Reductase Genes
Male pattern baldness is likely caused by multiple genes, not just 5α-reductase genes.
research 5α-Reductase Activity in the Human Hair Follicle Concentrates in the Dermal Papilla
The enzyme that changes testosterone to a stronger form is mostly found in the part of the hair follicle called the dermal papilla.
research Follicular Transplantation
Careful planning and patient counseling can lead to excellent hair transplant results, often in one or two sessions.
research Follicular Transplantation: Patient Evaluation and Surgical Planning
Follicular transplantation can greatly improve hair restoration if done with detailed planning and patient evaluation.
research Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia
People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.
research Elliptical Donor Stereoscopically Assisted Micrografting as an Approach to Further Refinement in Hair Transplantation
This hair transplant method improves cosmetic results for hair loss.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Diagnostic and Predictive Value of Horizontal Sections of Scalp Biopsy Specimens in Male Pattern Androgenetic Alopecia
Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.
research Steroid Chemistry and Hormone Controls During the Hair Follicle Cycle
Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.
research Acquired Progressive Kinking of Hair
Acquired Progressive Kinking of Hair is likely an early sign of male pattern baldness.
research The Inheritance Of Common Baldness: To Be Or Not To Be?
Common baldness is likely inherited through multiple genes, not just one.
research Treatment of Severe Hypertension with Minoxidil: Advantages and Limitations
Minoxidil effectively controls blood pressure but side effects may limit its use.
research Classification of the Types of Androgenetic Alopecia (Common Baldness) Occurring in the Female Sex
Common baldness, also known as Androgenetic Alopecia, is caused by a combination of genetic factors and hormones called androgens.
research Male Pattern Alopecia: A Histopathologic and Histochemical Study
Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.