research Clinical and molecular genetic studies in hereditary hair loss
Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.
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research Multiple endocrine defects in adult-onset Sprouty1/2/4 triple knockout mice
Removing Sprouty genes in mice causes various hormone-related issues but does not increase cancer risk by one year of age.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Porcine acellular dermal matrix facilitates hair follicle stem cells entering the hair cycle in C57/BL6 mice
Porcine ADM scaffold helps hair growth in mice.
research Programmable viscoelastic hydrogels exhibit antimicrobial and regenerative properties to promote cell migration, wound healing, and tissue remodeling
HA-gel-dex hydrogels help heal wounds and regenerate tissue effectively.
research Post‐Traumatic Tress Disorder: Obama, Palin and Marie‐Antoinette
Stress does not greatly speed up aging or hair loss in politicians.
research Engineering the future of hair follicle regeneration and delivery
Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.
research Platelet-rich plasma in androgenetic alopecia
PRP can help treat hair loss but needs standardized methods for best results.
research Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.
research Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice
Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.
research The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate
The extracellular matrix is crucial for controlling skin stem cell behavior and health.
research The genetics of hair shaft disorders
The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.
research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles
Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.
research Alopecia Areata
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles
Certain genetic variants linked to immune response increase the risk of alopecia areata in Taiwanese people.
research Genome-wide detection of RNA editing events during the hair follicles cycle of Tianzhu white yak
RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.
research Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation
Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
research Mesenchymal Stromal Cell Secretome: Influencing Therapeutic Potential by Cellular Pre-conditioning
Changing how mesenchymal stromal cells are grown can improve their healing abilities.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.
research Stem cell markers (cytokeratin 15, CD34 and nestin) in primary scarring and nonscarring alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Developmental genetics of color pattern establishment in cats
Cat color patterns are determined early in development by gene expression and epidermal changes, with the Dickkopf 4 gene playing a crucial role.
research Epigenetic mechanism of Gtl2-miRNAs causes the primitive sheep characteristics found in purebred Merino sheep
A special gene region controls the re-emergence of a primitive wool type in Merino sheep, improving their wool yield and adaptability.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
research Proceedings of the Ninth World Congress for Hair Research (2015)
The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
research Hair growth promoting activity of discarded biocomposite keratin extract
Keratin extract from human hair was found to promote hair growth in mice.
research Formulation and Evaluation of Herbal Hair Gel for Hair Growth Potential
The herbal hair gel with Eclipta alba and Lippia nodiflora extracts was more effective at growing hair than the control gel and minoxidil.
research Gold thread implantation promotes hair growth in human and mice
Gold thread implantation may help hair grow in humans and mice.
research Neuronal plasticity of the “brain–skin connection”: stress-triggered up-regulation of neuropeptides in dorsal root ganglia and skin via nerve growth factor-dependent pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators
Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.