February 2013 in “Journal of The American Academy of Dermatology” Using hair loss drugs finasteride and dutasteride may cause sexual side effects.
October 2025 in “Frontiers in Endocrinology” Methimazole for hyperthyroidism has known and new side effects needing more study for safety.
November 2021 in “Evidencia” Young patients using finasteride may have higher risks of anxiety, depression, and suicidal thoughts.
3 citations
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May 2025 in “Frontiers in Pharmacology” This study analyzed 7,733 adverse event reports for vismodegib from the FDA Adverse Event Reporting System to assess its safety profile in treating advanced basal cell carcinoma. Known adverse events such as muscle spasms, taste alterations, alopecia, fatigue, and weight loss were confirmed, while potential new adverse events like squamous cell carcinoma, dehydration, and dysphagia were identified. The median onset for these events was 69 days after starting treatment, emphasizing the need for close monitoring, especially in the first 2 months. The findings enhance understanding of vismodegib's safety in real-world settings, aiding in its informed use in clinical practice.
July 2018 in “Reactions Weekly” Lower finasteride doses had more side effects; dutasteride caused back pain; more research needed on post-finasteride syndrome.
June 2024 in “Journal of Clinical Oncology” EGFR-TKIs can cause unexpected skin, nail, and hair issues.
January 2020 in “Figshare” The study explored a possible link between finasteride use and suicide.
July 2025 in “Journal of Investigative Dermatology” Some sunscreen ingredients may be linked to hair loss, but more research is needed.
December 2021 in “OPAL (Open@LaTrobe) (La Trobe University)” Montelukast is linked to increased risks of suicidal thoughts and depression.
1 citations
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May 2021 in “JAMA Dermatology” Finasteride use may be linked to hair loss, depression, anxiety, and suicidal thoughts.
August 2018 in “Journal of The American Academy of Dermatology” The conclusion is that finasteride is linked to an increased risk of suicidal thoughts and a higher risk of completed suicide when used for hair loss.
12 citations
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June 2019 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” Proper skin toxicity management in chemotherapy is key to continuing treatment and keeping patient quality of life high.
5 citations
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July 2019 in “Journal of Cutaneous Medicine and Surgery” Isotretinoin may cause hair loss, especially in women and young adults.
1 citations
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May 2021 in “Scientific Reports” Certain cancer drugs are strongly linked to nerve damage, requiring close monitoring and early treatment.
35 citations
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June 2018 in “Urology” The review suggests younger men taking 1 mg finasteride report more side effects, including sexual, skin, metabolic, and psychological issues.
2 citations
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January 2021 in “Journal of The American Academy of Dermatology” Low-dose oral minoxidil for hair loss seems to have rare side effects, but more research is needed to confirm its safety.
July 2023 in “Skin health and disease” Most UK survey participants had negative side effects from botulinum toxin injections, with many not fully recovering physically, emotionally, or financially.
Oral minoxidil may have more cardiovascular risks than topical minoxidil.
52 citations
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May 2013 in “Supportive Care in Cancer” Scalp cooling significantly reduces hair loss in chemotherapy patients.
April 2015 in “Reactions Weekly” Finasteride toxicity information is limited, poor quality, and biased.
6 citations
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February 2025 in “BMC Medical Research Methodology” Inconsistent safety reporting in chronic back pain trials risks patient safety and decision-making.
Certain drugs, especially those for eyes, bacterial infections, imaging tests, and skin conditions, are more likely to cause itching, with differences seen across gender, age, and weight.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Current drug safety systems fail to detect long-term side effects, needing improvements to protect health and trust.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Current drug safety systems fail to detect long-term side effects, leading to preventable health issues.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Post-drug syndromes are often overlooked, and better systems and education are needed to improve drug safety.
35 citations
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January 2010 in “British Journal of Clinical Pharmacology” Saw Palmetto can cause severe liver damage.
8 citations
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March 2019 in “Drugs - Real World Outcomes” Healthcare claims databases can help monitor drug safety, but may report adverse events differently than direct surveillance.
1 citations
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October 2025 in “Scientific Reports” Sonidegib and vismodegib have different side effects and reporting patterns.
18 citations
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June 2017 in “Oncotarget” Digoxin is linked to a higher risk of anemia in patients with atrial fibrillation and heart failure.
Certain medications, especially 5-alpha reductase inhibitors, are commonly linked to erectile dysfunction.