October 2025 in “JURNAL BIOLOGI TROPIS” Androgenetic alopecia is common hair loss due to genetics and hormones, manageable with early treatment.
April 2023 in “Journal of Investigative Dermatology” Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
November 2022 in “Journal of Investigative Dermatology” Skin aging and cancer development are influenced by the competition between stem cells.
September 1998 in “Journal of The European Academy of Dermatology and Venereology” Aging can lead to poorer scalp and hair health, including less hair and more scalp diseases, which should be managed to help older people feel better.
March 2025 in “Aging Cell” Reducing IGF-1 can help rejuvenate hair follicles and prevent hair graying and loss.
January 2023 in “Dermatology” Ageing and increased senescent cells significantly contribute to common hair loss.
3 citations
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October 2023 in “Cosmetics” Healthy lifestyle changes can significantly improve skin health as you age.
240 citations
,
April 2011 in “Pigment Cell & Melanoma Research” Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
158 citations
,
June 2017 in “Maturitas” Estrogen helps improve skin aging and healing, especially in post-menopausal women.
73 citations
,
July 2016 in “Cosmetics” Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.
67 citations
,
June 2018 in “Engineering in Life Sciences” Plant cell culture is a promising method for creating sustainable and high-quality cosmetic ingredients.
45 citations
,
August 2023 in “Trends in Cell Biology” Controlling cellular changes can enable safe rejuvenation without cancer risk.
30 citations
,
July 2017 in “BioEssays” Activating NRF2 might help treat hair disorders by improving antioxidant defenses.
20 citations
,
February 2019 in “Genes” The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.
13 citations
,
January 2021 in “RSC chemical biology” Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
10 citations
,
October 2015 in “Medicina Clínica (english Edition)” Recombinant human epidermal growth factor is versatile, effective, and safe for long-term skin and mucosal treatments.
6 citations
,
September 2021 in “Autophagy” Autophagy prevents early aging and maintains lipid and pheromone balance in mouse glands.
5 citations
,
April 2021 in “Journal of Endocrinological Investigation” Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.
1 citations
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June 2022 in “Experimental dermatology” The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.
April 2026 in “Journal of Clinical Medicine” GLP-1 RAs may help wound healing but can also cause faster facial aging and skin issues.
February 2026 in “American Scientific Research Journal for Engineering, Technology, and Sciences (Global Society of Scientific Research and Researchers)” Gray hair requires special coloring techniques and care to maintain quality and strength.
November 2025 in “Free Radical Biology and Medicine” SOD1 and KL are promising targets for new hair loss treatments.
April 2024 in “BMB Reports” Lack of Cisd2 disrupts calcium balance in cells, leading to poorly functioning neutrophils.
January 2024 in “Journal Of Advanced Zoology” PRP's effectiveness in healing is unclear and needs more research.
August 2015 in “Free Radical Biology and Medicine” Nrf2 helps protect skin from damage but too much can cause skin problems.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
PTHrP is important for bone formation and may be targeted for osteoporosis treatment and longevity therapies.
January 2021 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Aging affects the cells around hair follicles, which may influence female pattern hair loss and treatment options.
6 citations
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December 2016 in “Springer eBooks” Environmental stressors like UV radiation, pollution, and extreme temperatures can damage skin and lead to diseases and aging.
January 2025 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” Age-related hair loss is linked to changes in blood vessels, stem cells, and aging cells, and understanding these can help keep hair healthy as we age.